2 November 2021
Malmö FF – Chelsea FC
Referee: Felix Brych (GER, photo)
Assistant Referee 1: Mark Borsch (GER)
Assistant Referee 2: Stefan Lupp (GER)
Fourth Official: Daniel Schlager (GER)
VAR: Sascha Stegemann (GER)
AVAR: Willy Delajod (FRA)
Referee Observer: Elmir Pilav (BIH)
VfL Wolfsburg – FC Salzburg
Referee: Artur Soares Dias (POR)
Assistant Referee 1: Rui Tavares (POR)
Assistant Referee 2: Paulo Soares (POR)
Fourth Official: Miguel Moreira (POR)
VAR: Joao Pinheiro (POR)
AVAR: François Letexier (FRA)
Referee Observer: Ichko Lozev (BUL)
Dynamo Kyiv – FC Barcelona
Referee: Ovidiu Hațegan (ROU)
Assistant Referee 1: Mircea Grigoriu (ROU)
Assistant Referee 2: Sebastian Gheorghe (ROU)
Fourth Official: Radu Petrescu (ROU)
VAR: Marco Di Bello (ITA)
AVAR: Maurizio Mariani (ITA)
Referee Observer: Uno Tutk (EST)
Bayern München – SL Benfica
Referee: Szymon Marciniak (POL)
Assistant Referee 1: Pawel Sokolnicki (POL)
Assistant Referee 2: Tomasz Listkiewicz (POL)
Fourth Official: Tomasz Musial (POL)
VAR: Tomasz Kwiatkowski (POL)
AVAR: Basrtosz Frankowski (POL)
Referee Observer: Kyros Vassaras (GRE)
Villarreal CF – BSC Young Boys
Referee: Serdar Gözübüyük (NED)
Assistant Referee 1: Joost Van Zuilen (NED)
Assistant Referee 2: Johan Balder (NED)
Fourth Official: Jeroen Manschot (NED)
VAR: Jochem Kamphuis (NED)
AVAR: Pol van Boekel (NED)
Referee Observer: Pascal Garibian (FRA)
Atalanta BC – Manchester United
Referee: Slavko Vinčić (SVN)
Assistant Referee 1: Tomaž Klančnik (SVN)
Assistant Referee 2: Andraž Kovačič (SVN)
Fourth Official: Matej Jug (SVN)
VAR: Bastian Dankert (GER)
AVAR: Christian Dingert (GER)
Referee Observer: Herbert Fandel (GER)
Sevilla FC – LOSC Lille
Referee: Istvan Kovacs (ROU)
Assistant Referee 1: Vasile Marinescu (ROU)
Assistant Referee 2: Mihai Artene (ROU)
Fourth Official: Horatiu Fesnic (ROU)
VAR: Marco Guida (ITA)
AVAR: Massimiliano Irrati (ITA)
Referee Observer: Nicola Rizzoli (ITA)
Juventus – FC Zenit
Referee: Alejandro Hernandez Hernandez (ESP)
Assistant Referee 1: Jose Naranjo Perez (ESP)
Assistant Referee 2: Teodoro Sobrino Magan (ESP)
Fourth Official: Jose Munuera Montero (ESP)
VAR: Juan Martinez Munuera (ESP)
AVAR: Ricardo De Burgos Bengoetxea (ESP)
Referee Observer: William Young (SCO)
3 November 2021
AC Milan – FC Porto
Referee: Clement Turpin (FRA)
Assistant Referee 1: Nicolas Danos (FRA)
Assistant Referee 2: Cyril Gringore (FRA)
Fourth Official: Jerôme Brisard (FRA)
VAR: François Letexier (FRA)
AVAR: Bastian Dankert (GER)
Referee Observer: Karen Nalbandyan (ARM)
Real Madrid – Shakhtar Donetsk
Referee: Benoît Bastien (FRA)
Assistant Referee 1: Aurelien Berthomieu (FRA)
Assistant Referee 2: Benjamin Pages (FRA)
Fourth Official: Jeremie Pignard (FRA)
VAR: Willy Delajod (FRA)
AVAR: Sascha Stegemann (GER)
Referee Observer: Roberto Rosetti (ITA)
Manchester City – Club Brugge
Referee: Antonio Mateu Lahoz (ESP)
Assistant Referee 1: Pau Cebrian Devis (ESP)
Assistant Referee 2: Roberto Diaz Perez (ESP)
Fourth Official: Santiago Jaime Latre (ESP)
VAR: Ricardo De Burgos Bengoetxea (ESP)
AVAR: Christian Dingert (GER)
Referee Observer: Francesco Bianchi (SUI)
RB Leipzig – Paris St. Germain
Referee: Andreas Ekberg (SWE)
Assistant Referee 1: Mehmet Culum (SWE)
Assistant Referee 2: Stefan Hallberg (SWE)
Fourth Official: Fredrik Klitte (SWE)
VAR: Massimiliano Irrati (ITA)
AVAR: Marco Guida (ITA)
Referee Observer: Leslie Irvine (NIR)
Liverpool FC – Atletico de Madrid
Referee: Danny Makkelie (NED)
Assistant Referee 1: Hessel Steegstra (NED)
Assistant Referee 2: Jan de Vries (NED)
Fourth Official: Dennis Higler (NED)
VAR: Pol van Boekel (NED)
AVAR: Jochem Kamphuis (NED)
Referee Observer: Bertrand Layec (FRA)
Sporting CP – Beşiktaş JK
Referee: Sergei Karasev (RUS)
Assistant Referee 1: Igor Demeshko (RUS)
Assistant Referee 2: Maksim Gavrilin (RUS)
Fourth Official: Kirill Levnikov (RUS)
VAR: Juan Martinez Munuera (ESP)
AVAR: Bartosz Frankowski (POL)
Referee Observer: Frank De Bleeckere (BEL)
Borussia Dortmund – AFC Ajax
Referee: Michael Oliver (ENG)
Assistant Referee 1: Stuart Burt (ENG)
Assistant Referee 2: Simon Bennett (ENG)
Fourth Official: Darren England (ENG)
VAR: Stuart Attwell (ENG)
AVAR: Tomasz Kwiatkowski (POL)
Referee Observer: Tomasz Mikulski (POL)
Sheriff Tiraspol – Inter Milano
Referee: Felix Zwayer (GER)
Assistant Referee 1: Rafael Foltyn (GER)
Assistant Referee 2: Marco Achmüller (GER)
Fourth Official: Sven Jablonski (GER)
VAR: Marco Fritz (GER)
AVAR: Harm Osmers (GER)
Referee Observer: Lucilio Batista (POR)