1 March 2016
DC United – Queretaro
Referee: John Pitti (PAN, photo)
Assistant Referee 1: Gabriel Victoria (PAN)
Assistant Referee 2: Ronald Bruna (PAN)
Fourth Official: Jafeth Perea (PAN)
Santos Laguna – LA Galaxy
Referee: Marlon Mejia (SLV)
Assistant Referee 1: Geovany Garcia (SLV)
Assistant Referee 2: Jose Mangandi (SLV)
Fourth Official: Jose Kellys (PAN)
2 March 2016
Club America – Seattle Sounders
Referee: Valdin Legister (JAM)
Assistant Referee 1: Kedlee Powell (JAM)
Assistant Referee 2: Garnet Page (JAM)
Fourth Official: Kevin Morrison (JAM)
Real Salt Lake – Tigres
Referee: Jeffrey Solis (CRC)
Assistant Referee 1: Leonel Leal (CRC)
Assistant Referee 2: Juan Mora (CRC)
Fourth Official: Walter Quesada (CRC)