12 October 2025
Ghana – Comoros
Referee: Pierre Atcho GAB
Assistant Referee 1: Boris Ditsoga GAB
Assistant Referee 2: Amos Ndong GAB
Fourth Official: Cregue Moukagni GAB
Zambia – Niger
Referee: Lucky Razake
Assistant Referee 1: Emmanuel Okudra
Assistant Referee 2: Hakim Mulindwa
Fourth Official: Dick Okello
Chad – Central African Republic
Referee: Celso Alvação MOZ
Assistant Referee 1: Arsenio Marengula MOZ
Assistant Referee 2: Ivanildo Lopes MOZ
Fourth Official: Simões Guambe MOZ
Egypt – Guinea Bissau
Referee: Daniel Laryea GHA
Assistant Referee 1: Roland Dodoo GHA
Assistant Referee 2: Theophilus Akugre GHA
Fourth Official: Abdul Adaari GHA
Djibouti – Sierra Leona
Referee: Thulani Sibandze
Assistant Referee 1: Thwala Banele
Assistant Referee 2: Ndumiso Magagula
Fourth Official: Celumusa Siphepho
Burkina Faso – Ethiopia
Referee: Adalbert Diouf SEN
Assistant Referee 1: Mamadou Ngom SEN
Assistant Referee 2: Amadou Ngom SEN
Fourth Official: Daouda Gueye SEN
Mali – Madagascar
Referee: Georges Gatogato
Assistant Referee 1: Emery Niyongabo
Assistant Referee 2: Rénovat Bizumuremyi
Fourth Official: Rodrigue Bigirimana
13 October 2025
South Sudan – Togo
Referee: Lamin Jammeh
Assistant Referee 1: Mustapha Bojang
Assistant Referee 2: Abass Bah
Fourth Official: Mohamed Marigo
Tunisia – Namibia
Referee: Issa Sy SEN
Assistant Referee 1: Djibril Camara SEN
Assistant Referee 2: Nouha Bangoura SEN
Fourth Official: El Hadji Sy SEN
