Ayacucho – Gremio
Referee: Esteban Ostojich (URU, photo)
Assistant Referee 1: Martin Soppi (URU)
Assistant Referee 2: Horacio Ferreiro (URU)
Fourth Official: Gustavo Tejera (URU)
Referee Assessor: Omar Ponce (ECU)
VAR Observer: Enrique Caceres (PAR)
Deportivo Lara – Santos
Referee: Victor Carrillo (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Michael Orue (PER)
Fourth Official: Joel Alarcon (PER)
Referee Assessor: Miguel Buitrago (VEN)
VAR Observer: Emerson De Carvalho (BRA)
Bolivar – Montevideo Wanderers
Referee: Guillermo Guerrero (ECU)
Assistant Referee 1: Byron Romero (ECU)
Assistant Referee 2: Juan Aguiar (ECU)
Fourth Official: Marlon Vera (ECU)
Referee Assessor: Juan Lugones (BOL)
VAR Observer: Jose Buitrago (COL)
Independiente Del Valle – Union Espanola
Referee: Wilmar Roldan (COL)
Assistant Referee 1: John Leon (COL)
Assistant Referee 2: Dionisio Ruiz (COL)
Fourth Official: Carlos Betancur (COL)
Referee Assessor: Wilson Avila (ECU)
VAR Observer: Dario Ubriaco (URU)
Libertad – Universidad Catolica
Referee: Fernando Rapallini (ARG)
Assistant Referee 1: Juan Belatti (ARG)
Assistant Referee 2: Diego Bonfa (ARG)
Fourth Official: Fernando Espinoza (ARG)
Referee Assessor: Amelio Andino (PAR)
VAR Observer: Roberto Silvera (URU)
San Lorenzo – Universidad de Chile
Referee: Leodan Gonzalez (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Richard Trinidad (URU)
Fourth Official: Christian Ferreyra (URU)
Referee Assessor: Hernan Maidana (ARG)
VAR Observer: Ubaldo Aquino (PAR)
Junior – Caracas
Referee: Mauro Vigliano (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Cristian Navarro (ARG)
Fourth Official: Fernando Echenique (ARG)
Referee Assessor: Abraham Gonzalez (COL)
VAR Observer: Carlos Torres (PAR)
Atletico Nacional – Guarani
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Gabriel Chade (ARG)
Assistant Referee 2: Julio Fernandez (ARG)
Fourth Official: Andres Merlos (ARG)
Referee Assessor: Jose Buitrago (COL)
VAR Observer: Nilson Moncao (BRA)
