25 June 2019
Cameroon – Guinea Bissau
Referee: Noureddine El-Jaafari (MAR, photo)
Assistant Referee 1: Lahcen Azgaou (MAR)
Assistant Referee 2: Mustapha Akarkad (MAR)
Fourth Official: Redouane Jiyed (MAR)
Ghana – Benin
Referee: Youssef Essrayri (TUN)
Assistant Referee 1: Yamen Mellouchi (TUN)
Assistant Referee 2: Ahmed Taha (EGY)
Fourth Official: Amin Omar (EGY)
26 June 2019
Nigeria – Guinea
Referee: Helder Martins (ANG)
Assistant Referee 1: Jerson Dos Santos (ANG)
Assistant Referee 2: Arsenio Marengula (MOZ)
Fourth Official: Beida Dahane (MTN)
Uganda – Zimbabwe
Referee: Eric Otogo Castane (GAB)
Assistant Referee 1: Issa Yaya (CHA)
Assistant Referee 2: Lionel Andrianantenaina (MAD)
Fourth Official: Mahamadou Keita (MLI)
Egypt – Congo
Referee: Victor Gomes (RSA)
Assistant Referee 1: Zakhele Siwela (RSA)
Assistant Referee 2: Souru Phatsoane (LES)
Fourth Official: Joshua Bondo (BOT)