Danubio – Deportivo Cali
Referee: Mauro Vigliano (ARG, photo)
Assistant Referee 1: Lucas Germanotta (ARG)
Assistant Referee 2: Julio Fernandez (ARG)
Fourth Official: Fernando Echenique (ARG)
Referee Assessor: Ana Oliveira (BRA)
Guabira – LDU Quito
Referee: Leodan Gonzalez (URU)
Assistant Referee 1: Miguel Nievas (URU)
Assistant Referee 2: Carlos Barreiro (URU)
Fourth Official: Jonathan Fuentes (URU)
Referee Assessor: Ricardo Casas (ARG)
Atletico Mineiro – San Lorenzo
Referee: Julio Bascuñan (CHI)
Assistant Referee 1: Carlos Astroza (CHI)
Assistant Referee 2: Christian Schiemann (CHI)
Fourth Official: Eduardo Gamboa (CHI)
Referee Assessor: Jose Buitrago (COL)
Deportes Temuco – Estudiantes Merida
Referee: Gustavo Murillo (COL)
Assistant Referee 1: Eduardo Diaz (COL)
Assistant Referee 2: Alexander Leon (COL)
Fourth Official: Carlos Betancur (COL)
Referee Assessor: Roberto Perassi (BRA)
Sao Paulo – Rosario Central
Referee: Eber Aquino (PAR)
Assistant Referee 1: Milciades Saldivar (PAR)
Assistant Referee 2: Carlos Caceres (PAR)
Fourth Official: Julio Quintana (PAR)
Referee Assessor: Jorge Larrionda (URU)
Botafogo – Audax Italiano
Referee: Michael Espinoza (PER)
Assistant Referee 1: Michael Orue (PER)
Assistant Referee 2: Stephen Atoche (PER)
Fourth Official: Luis Garay (PER)
Referee Assessor: Martin Vazquez (URU)
Boston River – Jaguares
Referee: Raul Orosco (BOL)
Assistant Referee 1: Jose Antelo (BOL)
Assistant Referee 2: Ariel Guizada (BOL)
Fourth Official: Juan Nelio Garcia (BOL)
Referee Assessor: Joel Ruiz (PAR)
Newell's Old Boys – Atletico Paranaense
Referee: Carlos Orbe (ECU)
Assistant Referee 1: Ricardo Baren (ECU)
Assistant Referee 2: Edwin Bravo (ECU)
Fourth Official: Omar Ponce (ECU)
Referee Assessor: Ana Perez (PER)
Nacional Potosi – Fluminense
Referee: Esteban Ostojich (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Gabriel Popovits (URU)
Fourth Official: Gustavo Tejera (URU)
Referee Assessor: Cesar Escano (PER)
Independiente Medellin – Sol de America
Referee: Raphael Claus (BRA)
Assistant Referee 1: Rodrigo Correa (BRA)
Assistant Referee 2: Alessandro Rocha (BRA)
Fourth Official: Wagner Reway (BRA)
Referee Assessor: Hugo Munoz (CHI)
Bahia – Blooming
Referee: Juan Soto (VEN)
Assistant Referee 1: Carlos Lopez (VEN)
Assistant Referee 2: Elbis Gomez (VEN)
Fourth Official: Jesus Valenzuela (VEN)
Referee Assessor: Sabrina Lois (ARG)
Boston River – Jaguares
Referee: Raul Orosco (BOL)
Assistant Referee 1: Jose Antelo (BOL)
Assistant Referee 2: Ariel Guizada (BOL)
Fourth Official: Juan Nelio Garcia (BOL)
Referee Assessor: Joel Ruiz (PAR)
Newell's Old Boys – Atletico Paranaense
Referee: Carlos Orbe (ECU)
Assistant Referee 1: Ricardo Baren (ECU)
Assistant Referee 2: Edwin Bravo (ECU)
Fourth Official: Omar Ponce (ECU)
Referee Assessor: Ana Perez (PER)
Nacional Potosi – Fluminense
Referee: Esteban Ostojich (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Gabriel Popovits (URU)
Fourth Official: Gustavo Tejera (URU)
Referee Assessor: Cesar Escano (PER)
Independiente Medellin – Sol de America
Referee: Raphael Claus (BRA)
Assistant Referee 1: Rodrigo Correa (BRA)
Assistant Referee 2: Alessandro Rocha (BRA)
Fourth Official: Wagner Reway (BRA)
Referee Assessor: Hugo Munoz (CHI)
Bahia – Blooming
Referee: Juan Soto (VEN)
Assistant Referee 1: Carlos Lopez (VEN)
Assistant Referee 2: Elbis Gomez (VEN)
Fourth Official: Jesus Valenzuela (VEN)
Referee Assessor: Sabrina Lois (ARG)