Santiago Wanderers – Independiente Santa Fe
Referee: Jose Argote (VEN, photo)
Assistant Referee 1: Jorge Urrego (VEN)
Assistant Referee 2: Tulio Moreno (VEN)
Fourth Official: Marlon Escalante (VEN)
Referee Assessor: Manuel Bernal (PAR)
Banfield – Nacional
Referee: Enrique Caceres (PAR)
Assistant Referee 1: Juan Zorrilla (PAR)
Assistant Referee 2: Roberto Canete (PAR)
Fourth Official: Ulises Mereles (PAR)
Referee Assessor: Ana Paula Oliveira (BRA)
Vasco Da Gama – Jorge Wilstermann
Referee: Fernando Rapallini (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Gustavo Rossi (ARG)
Fourth Official: Mauro Vigliano (ARG)
Referee Assessor: Jose Buitrago (COL)
Atletico Junior – Guarani
Referee: Leodan Gonzalez (URU)
Assistant Referee 1: Mauricio Espinosa (URU)
Assistant Referee 2: Richard Trinidad (URU)
Fourth Official: Jonathan Fuentes (URU)
Referee Assessor: Paulo Silva (ARG)
Second Leg, 20-22 February 2018
Independiente Santa Fe – Santiago Wanderers
Referee: Víctor Carrillo (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Coty Carrera (PER)
Fourth Official: Diego Haro (PER)
Referee Assessor: Sandro Vera (ECU)
Nacional – Banfield
Referee: Sandro Ricci (BRA)
Assistant Referee 1: Emerson De Carvalho (BRA)
Assistant Referee 2: Marcelo Van Gasse (BRA)
Fourth Official: Raphael Claus (BRA)
Referee Assessor: Jorge Jaimes (PER)
Jorge Wilstermann – Vasco Da Gama
Referee: Wilmar Roldán (COL)
Assistant Referee 1: Alexander Guzmán (COL)
Assistant Referee 2: Cristian De La Cruz (COL)
Fourth Official: Carlos Betancur (COL)
Referee Assessor: Juan Cardellino (URU)
Guaraní – Junior
Referee: Néstor Pitana (ARG)
Assistant Referee 1: Hernan Maidana (ARG)
Assistant Referee 2: Juan Belatti (ARG)
Fourth Official: Jorge Baliño (ARG)
Referee Assessor: Roberto Perassi (BRA)