17 October 2017
Red Bull Salzburg – Girondins Bordeaux
Referee: Sascha Amhof (SUI, photo)
Assistant Referee 1: Jean-Yves Wicht (SUI)
Assistant Referee 2: Devis Dettamanti (SUI)
Fourth Official: Sebastian Gishamer (AUT)
Referee Observer: Fritz Stuchlik (AUT)
Shkëndija – Nitra
Referee: Zaven Hovhannisyan (ARM)
Assistant Referee 1: Mesrop Ghazaryan (ARM)
Assistant Referee 2: Vanik Simonyan (ARM)
Fourth Official: Konstantin Vlaho (MKD)
Referee Observer: Emil Božinovski (MKD)
Shakhtsyor Salihorsk – FK Liepāja
Referee: Kirill Levnikov (RUS)
Assistant Referee 1: Viacheslav Semenov (RUS)
Assistant Referee 2: Dmitri Safyan (RUS)
Fourth Official: Viktar Shymusik (BLR)
Referee Observer: Aleh Chykun (BLR)
Legia Warszawa – Breidablik
Referee: Dejan Jakimovski (MKD)
Assistant Referee 1: Nikola Karakolev (MKD)
Assistant Referee 2: Kushtrim Lika (MKD)
Fourth Official: Piotr Urban (POL)
Referee Observer: Marcin Borski (POL)
Ajax – Hammarby
Referee: Nicolas Laforge (BEL)
Assistant Referee 1: Karel De Rocker (BEL)
Assistant Referee 2: Kevin Monteny (BEL)
Fourth Official: Jochem Kamphuis (NED)
Referee Observer: René Temmink (NED)
18 October 2017
Dynamo Kyiv – Internazionale Milano
Referee: George Găman (ROU)
Assistant Referee 1: Mircea Grigoriu (ROU)
Assistant Referee 2: Mihai Marica (ROU)
Fourth Official: Mykola Kryvonosov (UKR)
Referee Observer: Volodymyr Petrov (UKR)
Esbjerg – Käpylän Pallo
Referee: Aleksandrs Golubevs (LVA)
Assistant Referee 1: Raimonds Tatriks (LVA)
Assistant Referee 2: Jevgēņijs Morozovs (LVA)
Fourth Official: Jørgen Burchardt (DEN)
Referee Observer: Jens Larsen (DEN)
Lokomotiva Zagreb – FC Dinamo
Referee: Ádám Farkas (HUN)
Assistant Referee 1: Gergő Vígh-Tarsonyi (HUN)
Assistant Referee 2: Balázs Szalai (HUN)
Fourth Official: Igor Pajač (CRO)
Referee Observer: Draženko Kovačić (CRO)
FC Krasnodar – Kairat Almaty
Referee: Jari Järvinen (FIN)
Assistant Referee 1: Sami Nykänen (FIN)
Assistant Referee 2: Veli-Matti Leppänen (FIN)
Fourth Official: Artem Chistyakov (RUS)
Referee Observer: Yuri Baskakov (RUS)
Sparta Praha – F91 Dudelange
Referee: Roomer Tarajev (EST)
Assistant Referee 1: Sten Klaasen (EST)
Assistant Referee 2: Egerd Pajustik (EST)
Fourth Official: Ondřej Berka (CZE)
Referee Observer: Václav Krondl (CZE)
Budapest Honvéd – FK Sutjeska
Referee: Michal Očenáš (SVK)
Assistant Referee 1: Michal Tomčík (SVK)
Assistant Referee 2: Andrej Hrmo (SVK)
Fourth Official: Ádám Németh (HUN)
Referee Observer: Vencel Tóth (HUN)
Maccabi Haifa – FK Brodarac
Referee: Enea Jorgji (ALB)
Assistant Referee 1: Orgest Grabova (ALB)
Assistant Referee 2: Nertil Bregasi (ALB)
Fourth Official: Yigal Frid (ISR)
Referee Observer: Shmuel Shteif (ISR)
Saburtalo – Bursaspor
Referee: Dumitru Muntean (MDA)
Assistant Referee 1: Sergiu Beșliu (MDA)
Assistant Referee 2: Veaceslav Sivaciov (MDA)
Fourth Official: Irakli Kvirikashvili (GEO)
Referee Observer: Kostadin Gerginov (BUL)
Željezničar – Ludogorets Razgrad
Referee: Anastássios Papapétrou (GRE)
Assistant Referee 1: Ioánnis Sípkas (GRE)
Assistant Referee 2: Vassílios Kamboúris (GRE)
Fourth Official: Haris Kaljanac (BIH)
Referee Observer: Rusmir Mrković (BIH)
KS Vllaznia – Zimbru Chișinău
Referee: Dimítris Massiás (CYP)
Assistant Referee 1: Mários Kalogírou (CYP)
Assistant Referee 2: Pávlos Georgíou (CYP)
Fourth Official: Eldorjan Hamiti (ALB)
Referee Observer: Albano Janku (ALB)
Molde – University Dublin
Referee: Anders Poulsen (DEN)
Assistant Referee 1: Elvis Boric (DEN)
Assistant Referee 2: Victor Skytte (DEN)
Fourth Official: Mads Skarsem (NOR)
Referee Observer: Jon Skjervold (NOR)