11 October 2016
Colombia – Uruguay
Referee: Nestor Pitana (ARG, photo)
Assistant Referee 1: Hernan Maidana (ARG)
Assistant Referee 2: Juan Belatti (ARG)
Fourth Official: Fernando Rapallini (ARG)
Referee Assessor: Enrique Osses (CHI)
Chile – Peru
Referee: Roddy Zambrano (ECU)
Assistant Referee 1: Luis Vera (ECU)
Assistant Referee 2: Juan Macias (ECU)
Fourth Official: Juan Albarracin (ECU)
Referee Assessor: Jorge Larrionda (URU)
Bolivia – Ecuador
Referee: Mario Diaz de Vivar (PAR)
Assistant Referee 1: Juan Zorrilla (PAR)
Assistant Referee 2: Milciades Saldivar (PAR)
Fourth Official: Julio Quintana (PAR)
Referee Assessor: Otalvaro Polanco (COL)
Argentina – Paraguay
Referee: Daniel Fedorczuk (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Miguel Nievas (URU)
Fourth Official: Oscar Rojas (URU)
Referee Assessor: Adrian Gomez (VEN)
Venezuela – Brazil
Referee: Victor Carrillo (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Raul Lopez (PER)
Fourth Official: Diego Haro (PER)
Referee Assessor: Pedro Saucedo (BOL)