Cerro Porteno – Deportes Tolima
Referee: Diego Abal (ARG, photo)
Assistant Referee 1: Hernan Maidana (ARG)Assistant Referee 2: Julio Fernandez (ARG)
Fourth Official: Mario De Vivar (PAR)
Referee Observer: Cecilio Bejarano (PAR)
Santa Fe – Real Garcilaso
Referee: Sandro Ricci (BRA)
Assistant Referee 1: Emerson Carvalho (BRA)
Assistant Referee 2: Alessandro Rocha (BRA)
Fourth Official: Wilson Lamouroux (COL)
Referee Observer: Guilermo Suarez (COL)
17 April 2013
Barcelona – Nacional
Referee: Antonio Arias (PAR)
Assistant Referee 1: Carlos Caceres (PAR)
Assistant Referee 2: Milciades Saldivar (PAR)
Fourth Official: Omar Ponce (ECU)
Referee Observer: Juan Corozo (ECU)
Toluca – Boca Juniors
Referee: Imer Machado (COL)
Assistant Referee 1: Wilmar Navarro (COL)
Assistant Referee 2: Wilson Berrio (COL)
Fourth Official: Marco Rodriguez (MEX)
Referee Observer: Oscar Trejo (MEX)
Arsenal Sarandi – The Strongest
Referee: Carlos Vera (ECU)
Assistant Referee 1: Christian Lescano (ECU)
Assistant Referee 2: Byron Romero (ECU)
Fourth Official: Diego Ceballos (ARG)
Referee Observer: Carlos Coradina (ARG)
Sao Paulo – Atletico Mineiro
Referee: Wilton Sampaio (BRA)
Assistant Referee 1: Kleber Lucio Gil (BRA)
Assistant Referee 2: Rodrigo Correa (BRA)
Fourth Official: Francisco Nascimento (BRA)
Referee Observer: Ednilson Corona (BRA)
18 April 2013
Libertad – Tigre
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Eduardo Diaz (COL)
Assistant Referee 2: Christian De La Cruz (COL)
Fourth Official: Julio Quintana (PAR)
Referee Observer: Juan Bernabe (PAR)
Sporting Cristal – Palmeiras
Referee: Enrique Osses (CHI)
Assistant Referee 1: Carlos Astroza (CHI)
Assistant Referee 2: Sergio Roman (CHI)
Fourth Official: Manuel Garay (PER)
Referee Observer: Alberto Tejada (PER)
Huachipato – Gremio
Referee: Martin Vazquez (URU)
Assistant Referee 1: Miguel Nievas (URU)
Assistant Referee 2: Nicolas Taran (URU)
Fourth Official: Eduardo Gamboa (CHI)
Referee Observer: Ivan Guerrero (CHI)
Fluminense – Caracas
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Ernesto Uziga (ARG)
Fourth Official: Marcelo Henrique (BRA)
Referee Observer: Armando Marques (BRA)