10 April 2012
Zamora – Arsenal
Referee: Julio Quintana (PAR, photo)
Assistant Referee 1: Carlos Caceres (PAR)
Assistant Referee 2: Cesar Franco (PAR)
Fourth Official: Mayker Gomez (VEN)
Deportivo Quito – Defensor Sporting
Referee: Victor Carrillo (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Raul Lopez (PER)
Fourth Official: Diego Lara (ECU)
Union Espanola – Bolivar
Referee: Heber Lopes (BRA)
Assistant Referee 1: Roberto Braatz (BRA)
Assistant Referee 2: Marcelo Van Gasse (BRA)
Fourth Official: Julio Bascunan (CHI)
Atletico Nacional – Penarol
Referee: Joaquin Antequera (BOL)
Assistant Referee 1: Efrain Castro (BOL)
Assistant Referee 2: Cesar Nistahuz (BOL)
Fourth Official: Luis Sanchez (COL)
11 April 2012
Chivas Guadalajara – Velez Sarsfield
Referee: Henry Gambetta (PER)
Assistant Referee 1: Cesar Escano (PER)
Assistant Referee 2: Jorge Yupanqui (PER)
Fourth Official: Jose Penaloza (MEX)
Nacional – Corinthians
Referee: Patricio Loustau (ARG)
Assistant Referee 1: Ernesto Uziga (ARG)
Assistant Referee 2: Ivan Nunez (ARG)
Fourth Official: Carlos Amarilla (PAR)
Fluminense – Boca Juniors
Referee: Dario Ubriaco (URU)
Assistant Referee 1: Carlos Pastorino (URU)
Assistant Referee 2: Carlos Changala (URU)
Fourth Official: Pericles Cortes (BRA)
12 April 2012
Flamengo – Lanus
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Abraham Gonzalez (COL)
Assistant Referee 2: Wilson Berrio (COL)
Fourth Official: Marcelo Henrique (BRA)
Olimpia – Emelec
Referee: Roberto Silvera (URU)
Assistant Referee 1: Mauricio Espinosa (URU)
Assistant Referee 2: Nicolas Taran (URU)
Fourth Official: Ulises Mereles (PAR)
Nacional – Vasco da Gama
Referee: Pablo Lunati (ARG)
Assistant Referee 1: Gustavo Esquivel (ARG)
Assistant Referee 2: Juan Belatti (ARG)
Fourth Official: Martin Vazquez (URU)
Alianza Lima – Libertad
Referee: Juan Soto (VEN)
Assistant Referee 1: Jorge Urrego (VEN)
Assistant Referee 2: Carlos Lopez (VEN)
Fourth Official: Manuel Garay (PER)