Colombia – Venezuela
Referee: Anderson Daronco (BRA)
Assistant Referee 1: Rodrigo Figueiredo (BRA)
Assistant Referee 2: Guilherme Camilo (BRA)
Fourth Official: Paulo Zanovelli (BRA)
VAR: Wagner Reway (BRA)
AVAR: Pablo Goncalves (BRA)
Referee Assessor: Victor Carrillo (PER)
Paraguay – Peru
Referee: Andres Matonte (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Martin Soppi (URU)
Fourth Official: Jose Burgos (URU)
VAR: Leodan Gonzalez (URU)
AVAR: Richard Trinidad (URU)
Referee Assessor: Jose Buitrago (COL)
Argentina – Ecuador
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Alexander Guzmán (COL)
Assistant Referee 2: Wilmar Navarro (COL)
Fourth Official: Carlos Ortega (COL)
VAR: John Perdomo (COL)
AVAR: John Leon (COL)
Referee Assessor: Dario Ubriaco (URU)
Uruguay – Chile
Referee: Dario Herrera (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Gabriel Chade (ARG)
Fourth Official: Nicolas Lamolina (ARG)
VAR: Mauro Vigliano (ARG)
AVAR: Jorge Balino (ARG)
Referee Assessor: Oscar Maldonado (BOL)
Brazil – Bolivia
Referee: Juan Benitez (PAR)
Assistant Referee 1: Eduardo Cardozo (PAR)
Assistant Referee 2: Milciades Saldivar (PAR)
Fourth Official: Jose Mendez (PAR)
VAR: Carlos Benitez (PAR)
AVAR: Rodney Aquino (PAR)
Referee Assessor: Hector Baldassi (ARG)