22-23 April 2022
Al Rayyan – FK Istiqlol
Referee: Kim Hee-Gon (KOR, photo)
Assistant Referee 1: Kwak Seung-Soon (KOR)
Assistant Referee 2: Bang Gi-Yeol (KOR)
Fourth Official: Kim Dae-Yong (KOR)
FC Nasaf – Al Sadd
Referee: Ma Ning (CHN)
Assistant Referee 1: Shi Xiang (CHN)
Assistant Referee 2: Cao Yi (CHN)
Fourth Official: Nasrullo Kabirov (TJK)
Sharjah FC – Al Hilal
Referee: Mohanad Sarray (IRQ)
Assistant Referee 1: Watheq Al Swaiedi (IRQ)
Assistant Referee 2: Ahmed Al Baghdadi (IRQ)
Fourth Official: Ilgiz Tantashev (UZB)
Al Faisaly – Al Wehdat
Referee: Kim Jong-Hyeok (KOR)
Assistant Referee 1: Park Gyun-Yong (KOR)
Assistant Referee 2: Yaqoub Al Mutairi (KUW)
Fourth Official: Thoriq Alkatiri (IDN)
Al Quwa – Al Jazira
Referee: Ahmed Al Kaf (OMA)
Assistant Referee 1: Abu Al Amri (OMA)
Assistant Referee 2: Rashid Al Ghaithi (OMA)
Fourth Official: Mahmood Al Majarafi (OMA)
Al Shabab – Mumbai City
Referee: Fu Ming (CHN)
Assistant Referee 1: Yusri Mohamad (MAS)
Assistant Referee 2: Palitha Hemathunga (SRI)
Fourth Official: Jansen Foo (SIN)
Al Ahli – Ahal
Referee: Shaun Evans (AUS)
Assistant Referee 1: Owen Goldrick (AUS)
Assistant Referee 2: Arun Pillai (IND)
Fourth Official: Ali Reda (LBN)
Al Gharafa – Foolad
Referee: Ryuji Sato (JPN)
Assistant Referee 1: Hiroshi Yamauchi (JPN)
Assistant Referee 2: Jun Mihara (JPN)
Fourth Official: Nazmi Nasaruddin (MAS)
Sepahan – Pakhtakor
Referee: Jumpei Iida (JPN)
Assistant Referee 1: Rawut Nakrit (THA)
Assistant Referee 2: Tanate Chuchuen (THA)
Fourth Official: Baraa Aisha (PAL)
Al Taawoun – Al Duhail
Referee: Hiroyuki Kimura (JPN)
Assistant Referee 1: Isao Nishihashi (JPN)
Assistant Referee 2: Takumi Takagi (JPN)
Fourth Official: Yusuke Araki (JPN)