Millonarios – Fluminense
Referee: Dario Herrera (ARG, photo)
Assistant Referee 1: Gabriel Chade (ARG)
Assistant Referee 2: Cristian Navarro (ARG)
Fourth Official: Pablo Echavarria (ARG)
Referee Assessor: Jose Buitrago (COL)
VAR Supervisor: Hernan Maidana (ARG)
Everton – Monagas
Referee: Ivo Mendez (BOL)
Assistant Referee 1: Jose Antelo (BOL)
Assistant Referee 2: Edwar Saavedra (BOL)
Fourth Official: Adriana Farfan (BOL)
Referee Assessor: Francisco Mondria (CHI)
VAR Supervisor: Roberto Silvera (URU)
Plaza Colonia – The Strongest
Referee: Bruno Arleu (BRA)
Assistant Referee 1: Marcelo Van Gasse (BRA)
Assistant Referee 2: Alessandro Rocha (BRA)
Fourth Official: Savio Sampaio (BRA)
Referee Assessor: Carlos Pastorino (URU)
VAR Supervisor: Freddy Arellanos (PER)
Bolivar – Universidad Catolica
Referee: Piero Maza (CHI)
Assistant Referee 1: Alejandro Molina (CHI)
Assistant Referee 2: Claudio Urrutia (CHI)
Fourth Official: Nicolas Gamboa (CHI)
Referee Assessor: Juan Lugones (BOL)
VAR Supervisor: Olga Miranda (PAR)
America Mineiro – Guarani
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Sebastian Vela (COL)
Assistant Referee 2: John Gallego (COL)
Fourth Official: Carlos Betancur (COL)
Referee Assessor: Nilson Moncao (BRA)
VAR Supervisor: Sabrina Lois (ARG)
Audax Italiano – Estudiantes La Plata
Referee: Christian Ferreyra (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Richard Trinidad (URU)
Fourth Official: Jose Burgos (URU)
Referee Assessor: Barbra Bastias (CHI)
VAR Supervisor: Abraham Gonzalez (COL)
Barcelona – Universitario
Referee: Jose Argote (VEN)
Assistant Referee 1: Carlos Lopez (VEN)
Assistant Referee 2: Lubin Torrealba (VEN)
Fourth Official: Angel Arteaga (VEN)
Referee Assessor: Juan Corozo (ECU)
VAR Supervisor: Ubaldo Aquino (PAR)
Olimpia – Atletico Nacional
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Facundo Rodriguez (ARG)
Fourth Official: Yael Falcon (ARG)
Referee Assessor: Manuel Bernal (PAR)
VAR Supervisor: Wilson Avila (ECU)