Venezuela – Ecuador
Referee: Roberto Tobar (CHI, photo)
Assistant Referee 1: Christian Schiemann (CHI)
Assistant Referee 2: Claudio Rios (CHI)
Fourth Official: Leodan Gonzalez (URU)
VAR: Julio Bascunan (CHI)
AVAR: Cristian Garay (CHI)
Referee Assessor: Ubaldo Aquino (PAR)
Colombia – Peru
Referee: Esteban Ostojich (URU)
Assistant Referee 1: Martin Soppi (URU)
Assistant Referee 2: Edwar Saavedra (BOL)
Fourth Official: Gery Vargas (BOL)
VAR: Andres Cunha (URU)
AVAR: Daniel Fedorczuk (URU)
Referee Assessor: Amelio Andino (PAR)
21 June 2021
Uruguay – Chile
Referee: Raphael Claus (BRA)
Assistant Referee 1: Christian Lescano (ECU)
Assistant Referee 2: Byron Romero (ECU)
Fourth Official: Guillermo Guerrero (ECU)
VAR: Rafael Traci (BRA)
AVAR: Victor Carrillo (PER)
Referee: Roberto Tobar (CHI, photo)
Assistant Referee 1: Christian Schiemann (CHI)
Assistant Referee 2: Claudio Rios (CHI)
Fourth Official: Leodan Gonzalez (URU)
VAR: Julio Bascunan (CHI)
AVAR: Cristian Garay (CHI)
Referee Assessor: Ubaldo Aquino (PAR)
Colombia – Peru
Referee: Esteban Ostojich (URU)
Assistant Referee 1: Martin Soppi (URU)
Assistant Referee 2: Edwar Saavedra (BOL)
Fourth Official: Gery Vargas (BOL)
VAR: Andres Cunha (URU)
AVAR: Daniel Fedorczuk (URU)
Referee Assessor: Amelio Andino (PAR)
21 June 2021
Uruguay – Chile
Referee: Raphael Claus (BRA)
Assistant Referee 1: Christian Lescano (ECU)
Assistant Referee 2: Byron Romero (ECU)
Fourth Official: Guillermo Guerrero (ECU)
VAR: Rafael Traci (BRA)
AVAR: Victor Carrillo (PER)
Referee Assessor: Roberto Perassi (BRA)
Argentina – Paraguay
Referee: Jesus Valenzuela (VEN)
Assistant Referee 1: Carlos Lopez (VEN)
Assistant Referee 2: Jorge Urrego (VEN)
Fourth Official: Alexis Herrera (VEN)
VAR: John Ospina (COL)
AVAR: Alexander Guzman (COL)
Referee Assessor: Omar Ponce (ECU)