13 June 2021
Brazil – Venezuela
Referee: Esteban Ostojich (URU, photo)
Assistant Referee 1: Carlos Barreiro (URU)
Assistant Referee 2: Martin Soppi (URU)
Fourth Official: Gery Vargas (BOL)
VAR: Julio Bascunan (CHI)
AVAR: Cristian Garay (CHI)
Referee: Esteban Ostojich (URU, photo)
Assistant Referee 1: Carlos Barreiro (URU)
Assistant Referee 2: Martin Soppi (URU)
Fourth Official: Gery Vargas (BOL)
VAR: Julio Bascunan (CHI)
AVAR: Cristian Garay (CHI)
Referee Assessor: Enrique Caceres (PAR)
Colombia – Ecuador
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Gabriel Chade (ARG)
Fourth Official: Jesus Gil Manzano (ESP)
VAR: Mauro Vigliano (ARG)
AVAR: Facundo Tello (ARG)
Colombia – Ecuador
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Gabriel Chade (ARG)
Fourth Official: Jesus Gil Manzano (ESP)
VAR: Mauro Vigliano (ARG)
AVAR: Facundo Tello (ARG)
Referee Assessor: Ubaldo Aquino (PAR)
14 June 2021
Argentina – Chile
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Alexander Guzman (COL)
Assistant Referee 2: John Leon (COL)
Fourth Official: Alexis Herrera (VEN)
VAR: John Ospina (COL)
AVAR: Christian Lescano (ECU)
14 June 2021
Argentina – Chile
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Alexander Guzman (COL)
Assistant Referee 2: John Leon (COL)
Fourth Official: Alexis Herrera (VEN)
VAR: John Ospina (COL)
AVAR: Christian Lescano (ECU)
Referee Assessor: Roberto Perassi (BRA)
Paraguay – Bolivia
Referee: Diego Haro (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Raul Lopez (PER)
Fourth Official: Guillermo Guerrero (ECU)
VAR: Wagner Reway (BRA)
AVAR: Victor Carrillo (PER)
Paraguay – Bolivia
Referee: Diego Haro (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Raul Lopez (PER)
Fourth Official: Guillermo Guerrero (ECU)
VAR: Wagner Reway (BRA)
AVAR: Victor Carrillo (PER)
Referee Assessor: Jose Buitrago (COL)