15 September 2015
Aguilas Doradas – Olimpia
Referee: Roddy Zambrano (ECU, photo)
Assistant Referee 1: Christian Lescano (ECU)
Assistant Referee 2: Byron Romero (ECU)
Fourth Official: Adrian Velez (COL)
Referee Observer: Pablo Montoya (COL)
Sportivo Luqueno – Deportivo La Guaira
Referee: Jonathan Fuentes (URU)
Assistant Referee 1: Carlos Pastorino (URU)
Assistant Referee 2: Richard Trinidad (URU)
Fourth Official: Mario Diaz De Vivar (PAR)
Referee Observer: Carlos Alarcon (PAR)
Universitario – Defensor Sporting
Referee: Omar Ponce (ECU)
Assistant Referee 1: Edwin Bravo (ECU)
Assistant Referee 2: Juan Macias (ECU)
Fourth Official: Luis Garay (PER)
Referee Observer: Antonio Arnao (PER)
16 September 2015
Huracan – Tigre
Referee: Jesus Valenzuela (VEN)
Assistant Referee 1: Luis Murillo (VEN)
Assistant Referee 2: Elbis Gomez (VEN)
Fourth Official: Pablo Diaz (ARG)
Referee Observer: Luis Bongianino (ARG)
Nacional – LDU Quito
Referee: Luiz Oliveira (BRA)
Assistant Referee 1: Marcelo Van Gasse (BRA)
Assistant Referee 2: Bruno Boschilia (BRA)
Fourth Official: Ulises Mereles (PAR)
Referee Observer: Ubaldo Aquino (PAR)
Santa Fe – Nacional
Referee: Mauro Vigliano (ARG)
Assistant Referee 1: Ernesto Uziga (ARG)
Assistant Referee 2: Ezequiel Brailovsky (ARG)
Fourth Official: Jose Buitrago (COL)
Referee Observer: Oscar Ruiz (COL)
Independiente – Arsenal
Referee: Andres Cunha (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Mauricio Espinosa (URU)
Fourth Official: Jorge Baliño (ARG)
Referee Observer: Carlos Coradina (ARG)
17 September 2015
Juventud – Emelec
Referee: Enrique Caceres (PAR)
Assistant Referee 1: Eduardo Cardozo (PAR)
Assistant Referee 2: Juan Zorrilla (PAR)
Fourth Official: Fernando Falce (URU)
Referee Observer: Gustavo Lopez (URU)
Junior – Deportes Tolima
Referee: Raphael Claus (BRA)
Assistant Referee 1: Emerson Carvalho (BRA)
Assistant Referee 2: Alessandro Rocha (BRA)
Fourth Official: Luis Sanchez (COL)
Referee Observer: Otalvaro Polanco (COL)
Libertad – Universidad Catolica
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Humberto Clavijo (COL)
Assistant Referee 2: Eduardo Diaz (COL)
Fourth Official: Julio Quintana (PAR)
Referee Observer: Manuel Bernal (PAR)
Lanus – Belgrano
Referee: Antonio Arias (PAR)
Assistant Referee 1: Milciades Saldivar (PAR)
Assistant Referee 2: Dario Gaona (PAR)
Fourth Official: Fernando Rapallini (ARG)
Referee Observer: Miguel Scime (ARG)