AZ Alkmaar – Crvena Zvezda
Referee: David Munro (SCO, photo)
Assistant Referee 1: Sean Carr (SCO)
Assistant Referee 2: Craig Ferguson (SCO)
Fourth Official: Richard Martens (NED)
Referee Observer: Ruud Bossen (NED)
26 October 2022
Galatasaray – Rukh Lviv
Referee: Sander van der Eijk (NED)
Assistant Referee 1: Rogier Honig (NED)
Assistant Referee 2: Rens Bluemink (NED)
Fourth Official: Mehmet Türkmen (TUR)
Referee Observer: Orhan Erdemir (TUR)
KF Apolonia – Hajduk Split
Referee: Ishmael Barbara (MLT)
Assistant Referee 1: Roberto Vella (MLT)
Assistant Referee 2: James Muscat (MLT)
Fourth Official: Kreshnik Cjapi (ALB)
Referee Observer: Plarent Kotherja (ALB)
Coleraine FC – KRC Genk
Referee: Mohammed Al-Emara (FIN)
Assistant Referee 1: Turkka Valjakka (FIN)
Assistant Referee 2: Juuso Mantere (FIN)
Fourth Official: Shane Andrews (NIR)
Referee Observer: John Ferry (NIR)
FC Ashdod – MTK Budapest
Referee: Amine Kourgheli (BLR)
Assistant Referee 1: Juryj Chomčanka (BLR)
Assistant Referee 2: Viktar Hiecikaŭ (BLR)
Fourth Official: Nael Odeh (ISR)
Referee Observer: Shmuel Shteif (ISR)
BSC Young Boys – AIK
Referee: Marian Barbu (ROU)
Assistant Referee 1: Ferencz Tunyogy (ROU)
Assistant Referee 2: Imre Bucsi (ROU)
Fourth Official: Luca Piccolo (SUI)
Referee Observer: Andreas Schluchter (SUI)
Panathinaikos – AS Trenčín
Referee: Gustavo Correia (POR)
Assistant Referee 1: Tiago da Costa (POR)
Assistant Referee 2: Paulo Bras (POR)
Fourth Official: Lazaros Rendifis (GRE)
Referee Observer: Georgios Bikas (GRE)
Hibernian – Nantes
Referee: Joonas Jaanovits (EST)
Assistant Referee 1: Aron Härsing (EST)
Assistant Referee 2: Neeme Neemlaid (EST)
Referee Observer: Kenneth Clark (SCO)
Referee: David Munro (SCO, photo)
Assistant Referee 1: Sean Carr (SCO)
Assistant Referee 2: Craig Ferguson (SCO)
Fourth Official: Richard Martens (NED)
Referee Observer: Ruud Bossen (NED)
26 October 2022
Galatasaray – Rukh Lviv
Referee: Sander van der Eijk (NED)
Assistant Referee 1: Rogier Honig (NED)
Assistant Referee 2: Rens Bluemink (NED)
Fourth Official: Mehmet Türkmen (TUR)
Referee Observer: Orhan Erdemir (TUR)
KF Apolonia – Hajduk Split
Referee: Ishmael Barbara (MLT)
Assistant Referee 1: Roberto Vella (MLT)
Assistant Referee 2: James Muscat (MLT)
Fourth Official: Kreshnik Cjapi (ALB)
Referee Observer: Plarent Kotherja (ALB)
Coleraine FC – KRC Genk
Referee: Mohammed Al-Emara (FIN)
Assistant Referee 1: Turkka Valjakka (FIN)
Assistant Referee 2: Juuso Mantere (FIN)
Fourth Official: Shane Andrews (NIR)
Referee Observer: John Ferry (NIR)
FC Ashdod – MTK Budapest
Referee: Amine Kourgheli (BLR)
Assistant Referee 1: Juryj Chomčanka (BLR)
Assistant Referee 2: Viktar Hiecikaŭ (BLR)
Fourth Official: Nael Odeh (ISR)
Referee Observer: Shmuel Shteif (ISR)
BSC Young Boys – AIK
Referee: Marian Barbu (ROU)
Assistant Referee 1: Ferencz Tunyogy (ROU)
Assistant Referee 2: Imre Bucsi (ROU)
Fourth Official: Luca Piccolo (SUI)
Referee Observer: Andreas Schluchter (SUI)
Panathinaikos – AS Trenčín
Referee: Gustavo Correia (POR)
Assistant Referee 1: Tiago da Costa (POR)
Assistant Referee 2: Paulo Bras (POR)
Fourth Official: Lazaros Rendifis (GRE)
Referee Observer: Georgios Bikas (GRE)
Hibernian – Nantes
Referee: Joonas Jaanovits (EST)
Assistant Referee 1: Aron Härsing (EST)
Assistant Referee 2: Neeme Neemlaid (EST)
Referee Observer: Kenneth Clark (SCO)