15-17 March 2022
Barcelona – America Mineiro
Referee: Patricio Loustau (ARG, photo)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Gabriel Chade (ARG)
Fourth Official: Nicolas Gallo (COL)
Referee Assessor: Jose Carpio (ECU)
VAR Supervisor: Roberto Silvera (URU)
Olimpia – Fluminense
Referee: Roberto Tobar (CHI)
Assistant Referee 1: Chrisitian Schiemann (CHI)
Assistant Referee 2: Claudio Rios (CHI)
Fourth Official: Nicolas Gamboa (CHI)
Referee Assessor: Ubaldo Aquino (PAR)
VAR Supervisor: Hector Baldassi (ARG)
Estudiantes La Plata – Everton
Referee: Jesus Valenzuela (VEN)
Assistant Referee 1: Jorge Urrego (VEN)
Assistant Referee 2: Tulio Moreno (VEN)
Fourth Official: Angel Arteaga (VEN)
Referee Assessor: Angel Sanchez (ARG)
VAR Supervisor: Roberto Perassi (BRA)
The Strongest – Universidad Catolica
Referee: Wilton Sampaio (BRA)
Assistant Referee 1: Rafael Alves (BRA)
Assistant Referee 2: Bruno Boschilia (BRA)
Fourth Official: Flavio de Souza (BRA)
Referee Assessor: Juan Lugones (BOL)
VAR Supervisor: Fredy Arellanos (PER)