Fluminense – Millonarios
Referee: Fernando Rapallini (ARG, photo)
Assistant Referee 1: Juan Belatti (ARG)
Assistant Referee 2: Diego Bonfa (ARG)
Fourth Official: Nicolas Lamolina (ARG)
Referee Assessor: Sergio Cristiano (BRA)
VAR Supervisor: Roberto Silvera (URU)
Monagas – Everton
Referee: Gery Vargas (BOL)
Assistant Referee 1: Carlos Tapia (BOL)
Assistant Referee 2: Ruben Flores (BOL)
Fourth Official: Dilio Rodriguez (BOL)
Referee Assessor: Marlon Escalante (VEN)
VAR Supervisor: Ubaldo Aquino (PAR)
The Strongest – Plaza Colonia
Referee: John Ospina (COL)
Assistant Referee 1: Dionisio Ruiz (COL)
Assistant Referee 2: Miguel Roldan (COL)
Fourth Official: Carlos Ortega (COL)
Referee Assessor: Juan Lugones (BOL)
VAR Supervisor: Olga Miranda (PAR)
Universidad Catolica – Bolivar
Referee: Raphael Claus (BRA)
Assistant Referee 1: Danilo Manis (BRA)
Assistant Referee 2: Rafael Alves (BRA)
Fourth Official: Flavio Souza (BRA)
Referee Assessor: Juan Albarracin (ECU)
VAR Supervisor: Jorge Jaimes (PER)
Guarani – America Mineiro
Referee: Facundo Tello (ARG)
Assistant Referee 1: Facundo Rodriguez (ARG)
Assistant Referee 2: Maximiliano del Yesso (ARG)
Fourth Official: Andres Merlos (ARG)
Referee Assessor: Oscar Viera (PAR)
VAR Supervisor: Sabrina Lois (ARG)
Estudiantes La Plata – Audax Italiano
Referee: Wilton Sampaio (BRA)
Assistant Referee 1: Bruno Pires (BRA)
Assistant Referee 2: Bruno Boschilia (BRA)
Fourth Official: Bruno Arleu (BRA)
Referee Assessor: Angel Sanchez (ARG)
VAR Supervisor: Juan Cardellino (URU)
Universitario – Barcelona
Referee: Andres Matonte (URU)
Assistant Referee 1: Martin Soppi (URU)
Assistant Referee 2: Carlos Barreiro (URU)
Fourth Official: Leodan Gonzalez (URU)
Referee Assessor: Fredy Arellanos (PER)
VAR Supervisor: Patricio Polic (CHI)
Atletico Nacional – Olimpia
Referee: Patricio Loustau (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Gabriel Chade (ARG)
Fourth Official: Laura Fortunato (ARG)
Referee Assessor: Abraham Gonzalez (COL)
VAR Supervisor: Hernan Maidana (ARG)