Concacaf Champions League 2022 – Round of 16 (Second Leg)

22-24 February 2022

CF Montreal – Club Santos
Referee: Juan Calderon (CRC, photo)
Assistant Referee 1: Juan Mora (CRC)
Assistant Referee 2: William Arrieta (CRC)
Fourth Official: William Anderson (PUR)
VAR: Chris Penso (USA)
AVAR: Guido Gonzalez (USA)

Club Leon – Guastatoya
Referee: Daneon Parchment (JAM)
Assistant Referee 1: Ojay Duhaney (JAM)
Assistant Referee 2: Iroots Appleton (ATG)
Fourth Official: Reon Radix (GRN)
VAR: Edvin Jurisevic (USA)
AVAR: Tristley Bassue (SKN)

New York FC – Santos de Guapiles
Referee: Fernando Guerrero (MEX)
Assistant Referee 1: Pablo Hernandez (MEX)
Assistant Referee 2: Alejandro Camarena (PAN)
Fourth Official: Guillermo Pacheco (MEX)
VAR: Fernando Hernandez (MEX)
AVAR: Oscar Macias (MEX)

Colorado Rapids – Comunicaciones FC
Referee: Diego Montano (MEX)
Assistant Referee 1: Jose Martinez (MEX)
Assistant Referee 2: Andres Hernandez (MEX)
Fourth Official: Daniel Quintero (MEX)
VAR: Cesar Ramos (MEX)
AVAR: Jorge Perez (MEX)

Pumas – Saprissa
Referee: Mario Escobar (GUA)
Assistant Referee 1: Caleb Wales (TRI)
Assistant Referee 2: Henri Pupiro (NCA)
Fourth Official: Julio Luna (GUA)
VAR: Drew Fischer (CAN)
AVAR: Oshane Nation (JAM)

Cruz Azul – Forge FC
Referee: Walter Lopez (GUA)
Assistant Referee 1: Rene Ochoa (GUA)
Assistant Referee 2: Luis Ventura (GUA)
Fourth Official: Sergio Reyna (GUA)
VAR: Jair Marrufo (USA)
AVAR: Alex Chilowicz (USA)

Saunders FC – Motagua
Referee: Ivan Barton (SLV)
Assistant Referee 1: David Moran (SLV)
Assistant Referee 2: Zachari Zeegelaar (SUR)
Fourth Official: Bryan Lopez (GUA)
VAR: Erick Miranda (MEX)
AVAR: Keylor Herrera (CRC)