Club Brugge – Manchester City
Referee: Istvan Kovacs (ROU, photo)
Assistant Referee 1: Vasile Marinescu (ROU)
Assistant Referee 2: Ovidiu Artene (ROU)
Fourth Official: Marian Barbu (ROU)
VAR: Paolo Valeri (ITA)
AVAR: Fedayi San (SUI)
Referee Observer: Lutz-Michael Fröhlich (GER)
Beşiktaş JK – Sporting CP
Referee: Slavko Vinčić (SVN)
Assistant Referee 1: Tomaž Klančnik (SVN)
Assistant Referee 2: Andraž Kovačič (SVN)
Fourth Official: Rade Obrenović (SVN)
VAR: Matej Jug (SVN)
AVAR: Jure Praprotnik (SVN)
Referee Observer: Sokol Jareci (ALB)
Paris St. Germain – RB Leipzig
Referee: Marco Guida (ITA)
Assistant Referee 1: Ciro Carbone (ITA)
Assistant Referee 2: Giorgio Peretti (ITA)
Fourth Official: Fabio Maresca (ITA)
VAR: Marco Di Bello (ITA)
AVAR: Stuart Attwell (ENG)
Referee Observer: David Fernandez Borbalan (ESP)
FC Porto – AC Milan
Referee: Felix Brych (GER)
Assistant Referee 1: Mark Borsch (GER)
Assistant Referee 2: Stefan Lupp (GER)
Fourth Official: Daniel Schlager (GER)
VAR: Marco Fritz (GER)
AVAR: Christopher Kavanagh (ENG)
Referee Observer: Levan Paniashvili (GEO)
Atletico de Madrid – Liverpool FC
Referee: Daniel Siebert (GER)
Assistant Referee 1: Rafael Foltyn (GER)
Assistant Referee 2: Lasse Koslowski (GER)
Fourth Official: Sven Jablonski (GER)
VAR: Bastian Dankert (GER)
AVAR: Willy Delajod (FRA)
Referee Observer: Terje Hauge (NOR)
AFC Ajax – Borussia Dortmund
Referee: Jesus Gil Manzano (ESP)
Assistant Referee 1: Inigo Prieto Lopez (ESP)
Assistant Referee 2: Angel Nevado Rodriguez (ESP)
Fourth Official: Jose Munuera Montero (ESP)
VAR: Alejandro Hernandez Hernandez (ESP)
AVAR: Ricardo De Burgos Bengoechea (ESP)
Referee Observer: Hugh Dallas (SCO)
Inter Milano – Sheriff Tiraspol
Referee: Danny Makkelie (NED)
Assistant Referee 1: Hessel Steegstra (NED)
Assistant Referee 2: Jan de Vries (NED)
Fourth Official: Joey Kooij (NED)
VAR: Jochem Kamphuis (NED)
AVAR: Pol van Boekel (NED)
Referee Observer: William Young (SCO)
Shakhtar Donetsk – Real Madrid
Referee: Srdjan Jovanović (SRB)
Assistant Referee 1: Uroš Stojković (SRB)
Assistant Referee 2: Milan Mihajlović (SRB)
Fourth Official: Novak Simović (SRB)
VAR: Christian Dingert (GER)
AVAR: Harm Osmers (GER)
Referee Observer: Martin Ingvarsson (SWE)
20 October 2021
FC Barcelona – Dynamo Kyiv
Referee: Clement Turpin (FRA)
Assistant Referee 1: Nicolas Danos (FRA)
Assistant Referee 2: Cyril Gringore (FRA)
Fourth Official: Jeremie Pignard (FRA)
VAR: Willy Delajod (FRA)
AVAR: Marco Di Bello (ITA)
Referee Observer: Alexandru Deaconu (ROU)
FC Salzburg – VfL Wolfsburg
Referee: Daniele Orsato (ITA)
Assistant Referee 1: Alessandro Giallatini (ITA)
Assistant Referee 2: Fabiano Preti (ITA)
Fourth Official: Daniele Doveri (ITA)
VAR: Massimiliano Irrati (ITA)
AVAR: Paolo Valeri (ITA)
Referee Observer: Boško Jovanetić (SRB)
SL Benfica – Bayern München
Referee: Ovidiu Hategan (ROU)
Assistant Referee 1: Radu Ghinguleac (ROU)
Assistant Referee 2: Sebastian Gheorghe (ROU)
Fourth Official: Marcel Birsan (ROU)
VAR: Pol van Boekel (NED)
AVAR: Jochem Kamphuis (NED)
Referee Observer: Konrad Plautz (AUT)
BSC Young Boys – Villarreal CF
Referee: Sergei Karasev (RUS)
Assistant Referee 1: Igor Demeshko (RUS)
Assistant Referee 2: Maksim Gavirlin (RUS)
Fourth Official: Aleksei Kulbakov (BLR)
VAR: Vitali Meshkov (RUS)
AVAR: Christopher Kavanagh (ENG)
Referee Observer: Costas Kapitanis (CYP)
Manchester United – Atalanta BC
Referee: Szymon Marciniak (POL)
Assistant Referee 1: Pawel Sokolnicki (POL)
Assistant Referee 2: Tomasz Listkiewicz (POL)
Fourth Official: Tomasz Musial (POL)
VAR: Tomasz Kwiatkowski (POL)
AVAR: Marco Fritz (GER)
Referee Observer: Jorn West Larsen (DEN)
LOSC Lille – Sevilla FC
Referee: Michael Oliver (ENG)
Assistant Referee 1: Stuart Burt (ENG)
Assistant Referee 2: Simon Peter Bennett (ENG)
Fourth Official: David Coote (ENG)
VAR: Stuart Attwell (ENG)
AVAR: Paul Tierney (ENG)
Referee Observer: Raymond Ellingham (WAL)
FC Zenit – Juventus
Referee: Sandro Schärer (SUI)
Assistant Referee 1: Stephane De Almeida (SUI)
Assistant Referee 2: Bekim Zogaj (SUI)
Fourth Official: Alain Bieri (SUI)
VAR: Bastian Dankert (GER)
AVAR: Fedayi San (SUI)
Referee Observer: Emil Bozhinovski (MKD)
Chelsea FC – Malmö FF
Referee: François Letexier (FRA)
Assistant Referee 1: Cyril Mugnier (FRA)
Assistant Referee 2: Mehdi Rahmouni (FRA)
Fourth Official: Thomas Leonard (FRA)
VAR: Alejandro Hernandez Hernandez (ESP)
AVAR: Benoît Millot (FRA)
Referee Observer: Miroslav Tulinger (CZE)
Referee: Istvan Kovacs (ROU, photo)
Assistant Referee 1: Vasile Marinescu (ROU)
Assistant Referee 2: Ovidiu Artene (ROU)
Fourth Official: Marian Barbu (ROU)
VAR: Paolo Valeri (ITA)
AVAR: Fedayi San (SUI)
Referee Observer: Lutz-Michael Fröhlich (GER)
Beşiktaş JK – Sporting CP
Referee: Slavko Vinčić (SVN)
Assistant Referee 1: Tomaž Klančnik (SVN)
Assistant Referee 2: Andraž Kovačič (SVN)
Fourth Official: Rade Obrenović (SVN)
VAR: Matej Jug (SVN)
AVAR: Jure Praprotnik (SVN)
Referee Observer: Sokol Jareci (ALB)
Paris St. Germain – RB Leipzig
Referee: Marco Guida (ITA)
Assistant Referee 1: Ciro Carbone (ITA)
Assistant Referee 2: Giorgio Peretti (ITA)
Fourth Official: Fabio Maresca (ITA)
VAR: Marco Di Bello (ITA)
AVAR: Stuart Attwell (ENG)
Referee Observer: David Fernandez Borbalan (ESP)
FC Porto – AC Milan
Referee: Felix Brych (GER)
Assistant Referee 1: Mark Borsch (GER)
Assistant Referee 2: Stefan Lupp (GER)
Fourth Official: Daniel Schlager (GER)
VAR: Marco Fritz (GER)
AVAR: Christopher Kavanagh (ENG)
Referee Observer: Levan Paniashvili (GEO)
Atletico de Madrid – Liverpool FC
Referee: Daniel Siebert (GER)
Assistant Referee 1: Rafael Foltyn (GER)
Assistant Referee 2: Lasse Koslowski (GER)
Fourth Official: Sven Jablonski (GER)
VAR: Bastian Dankert (GER)
AVAR: Willy Delajod (FRA)
Referee Observer: Terje Hauge (NOR)
AFC Ajax – Borussia Dortmund
Referee: Jesus Gil Manzano (ESP)
Assistant Referee 1: Inigo Prieto Lopez (ESP)
Assistant Referee 2: Angel Nevado Rodriguez (ESP)
Fourth Official: Jose Munuera Montero (ESP)
VAR: Alejandro Hernandez Hernandez (ESP)
AVAR: Ricardo De Burgos Bengoechea (ESP)
Referee Observer: Hugh Dallas (SCO)
Inter Milano – Sheriff Tiraspol
Referee: Danny Makkelie (NED)
Assistant Referee 1: Hessel Steegstra (NED)
Assistant Referee 2: Jan de Vries (NED)
Fourth Official: Joey Kooij (NED)
VAR: Jochem Kamphuis (NED)
AVAR: Pol van Boekel (NED)
Referee Observer: William Young (SCO)
Shakhtar Donetsk – Real Madrid
Referee: Srdjan Jovanović (SRB)
Assistant Referee 1: Uroš Stojković (SRB)
Assistant Referee 2: Milan Mihajlović (SRB)
Fourth Official: Novak Simović (SRB)
VAR: Christian Dingert (GER)
AVAR: Harm Osmers (GER)
Referee Observer: Martin Ingvarsson (SWE)
20 October 2021
FC Barcelona – Dynamo Kyiv
Referee: Clement Turpin (FRA)
Assistant Referee 1: Nicolas Danos (FRA)
Assistant Referee 2: Cyril Gringore (FRA)
Fourth Official: Jeremie Pignard (FRA)
VAR: Willy Delajod (FRA)
AVAR: Marco Di Bello (ITA)
Referee Observer: Alexandru Deaconu (ROU)
FC Salzburg – VfL Wolfsburg
Referee: Daniele Orsato (ITA)
Assistant Referee 1: Alessandro Giallatini (ITA)
Assistant Referee 2: Fabiano Preti (ITA)
Fourth Official: Daniele Doveri (ITA)
VAR: Massimiliano Irrati (ITA)
AVAR: Paolo Valeri (ITA)
Referee Observer: Boško Jovanetić (SRB)
SL Benfica – Bayern München
Referee: Ovidiu Hategan (ROU)
Assistant Referee 1: Radu Ghinguleac (ROU)
Assistant Referee 2: Sebastian Gheorghe (ROU)
Fourth Official: Marcel Birsan (ROU)
VAR: Pol van Boekel (NED)
AVAR: Jochem Kamphuis (NED)
Referee Observer: Konrad Plautz (AUT)
BSC Young Boys – Villarreal CF
Referee: Sergei Karasev (RUS)
Assistant Referee 1: Igor Demeshko (RUS)
Assistant Referee 2: Maksim Gavirlin (RUS)
Fourth Official: Aleksei Kulbakov (BLR)
VAR: Vitali Meshkov (RUS)
AVAR: Christopher Kavanagh (ENG)
Referee Observer: Costas Kapitanis (CYP)
Manchester United – Atalanta BC
Referee: Szymon Marciniak (POL)
Assistant Referee 1: Pawel Sokolnicki (POL)
Assistant Referee 2: Tomasz Listkiewicz (POL)
Fourth Official: Tomasz Musial (POL)
VAR: Tomasz Kwiatkowski (POL)
AVAR: Marco Fritz (GER)
Referee Observer: Jorn West Larsen (DEN)
LOSC Lille – Sevilla FC
Referee: Michael Oliver (ENG)
Assistant Referee 1: Stuart Burt (ENG)
Assistant Referee 2: Simon Peter Bennett (ENG)
Fourth Official: David Coote (ENG)
VAR: Stuart Attwell (ENG)
AVAR: Paul Tierney (ENG)
Referee Observer: Raymond Ellingham (WAL)
FC Zenit – Juventus
Referee: Sandro Schärer (SUI)
Assistant Referee 1: Stephane De Almeida (SUI)
Assistant Referee 2: Bekim Zogaj (SUI)
Fourth Official: Alain Bieri (SUI)
VAR: Bastian Dankert (GER)
AVAR: Fedayi San (SUI)
Referee Observer: Emil Bozhinovski (MKD)
Chelsea FC – Malmö FF
Referee: François Letexier (FRA)
Assistant Referee 1: Cyril Mugnier (FRA)
Assistant Referee 2: Mehdi Rahmouni (FRA)
Fourth Official: Thomas Leonard (FRA)
VAR: Alejandro Hernandez Hernandez (ESP)
AVAR: Benoît Millot (FRA)
Referee Observer: Miroslav Tulinger (CZE)