Concacaf League 2021 – Round of 16 (First Leg)

21-23 September 2021

Forge FC – Independiente

Referee: Diego Montano (MEX, photo)

Assistant Referee 1: Miguel Hernandez (MEX)

Assistant Referee 2: Christian Espinosa (MEX)

Fourth Official: Adonai Escobedo (MEX)

Inter Moengo – Olimpia
Referee: Oliver Vergara (PAN)
Assistant Referee 1: Ronald Bruna (PAN)
Assistant Referee 2: Geovany Garcia (SLV)
Fourth Official: Jaime Herrera (SLV)

Guastatoya – Alajuelense
Referee: Nima Saghafi (USA)
Assistant Referee 1: Nicholas Uranga (USA)
Assistant Referee 2: Cameron Blanchard (USA)
Fourth Official: Joe Dickerson (USA)

Comunicaciones – Alianza
Referee: Jefferson Escobar (HON)
Assistant Referee 1: Walter Lopez (HON)
Assistant Referee 2: Gerson Orellana (HON)
Fourth Official: Selvin Brown (HON)

Marathon – Real Esteli
Referee: Tristley Bassue (SKN)
Assistant Referee 1: Kevon Clarke (BRB)
Assistant Referee 2: Iroots Appleton (ATG)
Fourth Official: Trevester Richards (SKN)

Universitario – Motagua
Referee: Julio Luna (GUA)
Assistant Referee 1: Julian Mendez (GUA)
Assistant Referee 2: Juan Tipaz (GUA)
Fourth Official: Oscar Reyna (GUA)

Santos de Guapiles – Plaza Amador
Referee: Tori Penso (USA)
Assistant Referee 1: Corey Rockwell (USA)
Assistant Referee 2: Ian Anderson (USA)
Fourth Official: Ted Unkel (USA)

Santa Lucia – Deportivo Saprissa
Referee: Randy Encarnacion (DOM)
Assistant Referee 1: Walter Cid (DOM)
Assistant Referee 2: Raymundo Feliz (DOM)
Fourth Official: Ricangel De Leca (ARU)