21 November 2017
Red Bull Salzburg – Sparta Praha
Referee: Mikhail Vilkov (RUS, photo)
Assistant Referee 1: Alexei Lebedev (RUS)
Assistant Referee 2: Alexei Vorontsov (RUS)
Fourth Official: Sebastian Gishamer (AUT)
Referee Observer: Konrad Plautz (AUT)
Ajax – Legia Warszawa
Referee: Mykola Balakin (UKR)
Assistant Referee 1: Viktor Matyash (UKR)
Assistant Referee 2: Volodymyr Vysotskyy (UKR)
Fourth Official: Jochem Kamphuis (NED)
Referee Observer: Rien Koopman (NED)
Nitra – Šachcior Salihorsk
Referee: Edin Jakupović (BIH)
Assistant Referee 1: Goran Dujak (BIH)
Assistant Referee 2: Damir Lazić (BIH)
Fourth Official: Marek Mastiš (SVK)
Referee Observer: Ján Fašung (SVK)
22 November 2017
Saburtalo – Brodarac
Referee: Ömər Paşayev (AZE)
Assistant Referee 1: Vaqif Musayev (AZE)
Assistant Referee 2: Cəmil Quliyev (AZE)
Fourth Official: Lasha Silagava (GEO)
Referee Observer: Sabri Çelik (TUR)
Budapest Honvéd – FC Krasnodar
Referee: Luís Teixeira (AND)
Assistant Referee 1: Bruno Fernandes (AND)
Assistant Referee 2: Andreu Vilanova (AND)
Fourth Official: Csaba Pintér (HUN)
Referee Observer: Ferenc Székely (HUN)
Esbjerg – Inter Milano
Referee: Ian McNabb (NIR)
Assistant Referee 1: Andrew Nethery (NIR)
Assistant Referee 2: Gavin Hegarty (NIR)
Fourth Official: Jørgen Daugbjerg (DEN)
Referee Observer: Jens Larsen (DEN)
FK Željezničar – Lokomotiva Zagreb
Referee: Juri Frischer (EET)
Assistant Referee 1: Silver Kõiv (EST)
Assistant Referee 2: Aron Härsing (EST)
Fourth Official: Haris Kaljanac (BIH)
Referee Observer: Elmir Pilav (BIH)
Molde FK – Zimbru Chișinău
Referee: Vilhjálmur Thórarinsson (ISL)
Assistant Referee 1: Frosti Gunnarsson (ISL)
Assistant Referee 2: Bryngeir Valdimarsson (ISL)
Fourth Official: Mads Skarsem (NOR)
Referee Observer: Kjell Alseth (NOR)