23 February 2016
Real Madrid – Manchester City
Referee: Marco Guida (ITA, photo)
Assistant Referee 1: Giacomo Paganessi (ITA)
Assistant Referee 2: Giorgio Peretti (ITA)
Fourth Official: Valentín Gómez (ESP)
Referee Observer: Juan Fernández Marin (ESP)
Chelsea – Valencia
Referee: Adrien Jaccottet (SUI)
Assistant Referee 1: Vital Jobin (SUI)
Assistant Referee 2: Marco Zürcher (SUI)
Fourth Official: Darren England (ENG)
Referee Observer: Stephen Lodge (ENG)
Barcelona – Midtjylland
Referee: Georgi Kabakov (BUL)
Assistant Referee 1: Martin Margaritov (BUL)
Assistant Referee 2: Martin Venev (BUL)
Fourth Official: David Medié Jiménez (ESP)
Referee Observer: Bernardino González Vázquez (ESP)
Anderlecht – Dinamo Zagreb
Referee: Andris Treimanis (LVA)
Assistant Referee 1: Haralds Gudermanis (LVA)
Assistant Referee 2: Aleksejs Spasjonnikovs (LVA)
Fourth Official: Wesley Alen (BEL)
Referee Observer: Frank De Bleeckere (BEL)
24 February 2016
PSV Eindhoven – AS Roma
Referee: Michael Tykgaard (DEN)
Assistant Referee 1: Dennis Rasmussen (DEN)
Assistant Referee 2: Amir Sabic (DEN)
Fourth Official: Jeroen Manschot (NED)
Referee Observer: Marinus Koopman (NED)
Paris St. Germain – Middlesbrough
Referee: Alexander Harkam (AUT)
Assistant Referee 1: Andreas Staudinger (AUT)
Assistant Referee 2: Robert Steinacher (AUT)
Fourth Official: Nicolas Dzubanowski (FRA)
Referee Observer: Ray Ellingham (WAL)
Lyon – Ajax
Referee: Kevin Clancy (SCO)
Assistant Referee 1: Sean Carr (SCO)
Assistant Referee 2: Douglas Potter (SCO)
Fourth Official: Hakim Ben El Hadj (FRA)
Referee Observer: Alain Hamer (LUX)
Príbram – Benfica
Referee: Sergei Ivanov (RUS)
Assistant Referee 1: Anton Averianov (RUS)
Assistant Referee 2: Igor Demeshko (RUS)
Fourth Official: Jiří Houdek (CZE)
Referee Observer: Miroslav Liba (CZE)