7 November 2012
Sao Paulo – Universidad de Chile
Referee: Enrique Caceres (PAR, photo)
Assistant Referee 1: Milciades Saldivar (PAR)
Assistant Referee 2: Hugo Martinez (PAR)
Fourth Official: Ulises Mereles (PAR)
Referee Observer: Aristeu Tavares (BRA)
8 November 2012
Universidad Catolica – Independiente
Referee: Victor Carrillo (PER)
Assistant Referee 1: Raul Lopez (PER)
Assistant Referee 2: Jorge Yupanqui (PER)
Fourth Official: Henry Gambetta (PER)
Referee Observer: Gaston Castro (CHI)
Tigre – Cerro Porteno
Referee: Martin Vazquez (URU)
Assistant Referee 1: Mauricio Espinoza (URU)
Assistant Referee 2: Carlos Changala (URU)
Fourth Official: Daniel Fedorczuk (URU)
Referee Observer: Abel Gnecco (ARG)
15 November 2012
Millonarios – Gremio
Referee: Carlos Vera (ECU)
Assistant Referee 1: Luis Alvarado (ECU)
Assistant Referee 2: Carlos Herrera (ECU)
Fourth Official: Diego Lara (ECU)
Referee Observer: Pablo Montoya (COL)