Millionarios – Intigas
Referee: Juan Soto (VEN, photo)
Assistant Referee 1: Jorge Urrego (VEN)
Assistant Referee 2: Carlos Lopez (VEN)
Fourth Official: Imer Machado (COL)
Cerro Largo – Aurora
Referee: Saul Laverni (ARG)
Assistant Referee 1: Gustavo Rossi (ARG)
Assistant Referee 2: Ernesto Uziga (ARG)
Fourth Official: Hector Martinez (URU)
Nacional – Iquique
Referee: Paulo Oliveira (BRA)
Assistant Referee 1: Carlos Berkenbrock (BRA)
Assistant Referee 2: Rodrigo Joia (BRA)
Fourth Official: Daniel Fedorczuk (URU)
15 August 2012
Liga de Loja – Monagas
Referee: Victor Carrillo (PER)
Assistant Referee 1: Johnny Bossio (PER)
Assistant Referee 2: Cesar Escano (PER)
Fourth Official: Roddy Zambrano (ECU)
Envigado – Union Comercio
Referee: Raul Orosco (BOL)
Assistant Referee 1: Efrain Castro (BOL)
Assistant Referee 2: Arol Valda (BOL)
Fourth Official: Juan Restrepo (COL)
16 August 2012
Universitario – Liverpool
Referee: Marlon Escalante (VEN)
Assistant Referee 1: Rafael Yanez (VEN)
Assistant Referee 2: Luis Murillo (VEN)
Fourth Official: Jose Jordan (BOL)
Argentinos Juniors – Tigre
Referee: Patricio Loustau (ARG)
Assistant Referee 1: Gustavo Esquivel (ARG)
Assistant Referee 2: Ivan Nunez (ARG)
Fourth Official: Federico Beligoy (ARG)
Deportivo Lara – Deportes Tolima
Referee: Diego Lara (ECU)
Assistant Referee 1: Luis Alvarado (ECU)
Assistant Referee 2: Christian Lescano (ECU)
Fourth Official: Jose Hoyo (VEN)
