31 July 2012
CS Herediano – Real Salt Lake
Referee: Francisco Chacon (MEX, photo)
Assistant Referee 1: Juan Rangel (MEX)
Assistant Referee 2: Miguel Vizcaya (MEX)
Fourth Official: Fabricio Morales (MEX)
CF Monterrey – Chorrillo
Referee: Hugo Cruz (CRC)
Assistant Referee 1: Leonel Leal (CRC)
Assistant Referee 2: Osvaldo Luna (CRC)
Fourth Official: Walter Quesada (CRC)
1 August 2012
Toronto FC – CD Aguila
Referee: Javier Santos (PUR)
Assistant Referee 1: Antonio Lopez (PUR)
Assistant Referee 2: Jairo Morales (PUR)
Fourth Official: Wilson Da Costa (BAH)
Isidro Metapan – Puerto Rico Islanders
Referee: Raul Castro (HON)
Assistant Referee 1: Oscar Velasquez (HON)
Assistant Referee 2: Christian Ramirez (HON)
Fourth Official: Erick Andino (HON)
Tigres UANL – Real Esteli
Referee: Paul Ward (CAN)
Assistant Referee 1: Daniel Belleau (CAN)
Assistant Referee 2: Darren Clark (CAN)
Fourth Official: David Gantar (CAN)
2 August 2012
W Connection – Xelaju
Referee: Marlon Mejia (SLV)
Assistant Referee 1: Douglas Bermudez (SLV)
Assistant Referee 2: Geovany Garcia (SLV)
Fourth Official: Ruben Medrano (SLV)
CD Olimpia – CD FAS
Referee: Jafeth Perea (PAN)
Assistant Referee 1: Jaime Smith (PAN)
Assistant Referee 2: Gabriel Victoria (PAN)
Fourth Official: Rolando Vidal (PAN)
Seattle Sounders – Caledonia AIA
Referee: Stanley Lancaster (GUY)
Assistant Referee 1: Dion Inniss (GUY)
Assistant Referee 2: Ricardo Louisville (SUR)
Fourth Official: Rudolph Angela (ARU)