6 March 2012
Penarol – Universidad de Chile
Referee: Omar Ponce (ECU, photo)
Assistant Referee 1: Juan Cedeno (ECU)
Assistant Referee 2: Carlos Herrera (ECU)
Fourth Official: Martin Vazquez (URU)
Vasco da Gama – Alianza Lima
Referee: Diego Abal (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Juan Belatti (ARG)
Fourth Official: Pericles Cortes (BRA)
Union Espanola – Universidad de Chile
Referee: Claudio Puga (CHI)
Assistant Referee 1: Julio Diaz (CHI)
Assistant Referee 2: Marcelo Barraza (CHI)
Fourth Official: Eduardo Gamboa (CHI)
7 March 2012
Santos – Internacional
Referee: Evandro Roman (BRA)
Assistant Referee 1: Dibert Pedrosa (BRA)
Assistant Referee 2: Rodrigo Joia (BRA)
Fourth Official: Ricardo Marques (BRA)
Deportivo Quito – Velez Sarsfield
Referee: Jose Buitrago (COL)
Assistant Referee 1: Humberto Clavijo (COL)
Assistant Referee 2: Alexander Guzman (COL)
Fourth Official: Roddy Zambrano (ECU)
Corinthians – Nacional
Referee: Enrique Osses (CHI)
Assistant Referee 1: Carlos Astroza (CHI)
Assistant Referee 2: Juan Maturana (CHI)
Fourth Official: Paulo Oliveira (BRA)
Boca Juniors – Fluminense
Referee: Carlos Amarilla (PAR)
Assistant Referee 1: Carlos Caceres (PAR)
Assistant Referee 2: Cesar Franco (PAR)
Fourth Official: German Delfino (ARG)
8 March 2012
Flamengo – Emelec
Referee: Dario Ubriaco (URU)
Assistant Referee 1: Carlos Pastorino (URU)
Assistant Referee 2: Nicolas Taran (URU)
Fourth Official: Marcelo Henrique (BRA)
Godoy Cruz – Atletico Nacional
Referee: Leandro Vuaden (BRA)
Assistant Referee 1: Alessandro Rocha (BRA)
Assistant Referee 2: Emerson Carvalho (BRA)
Fourth Official: Saul Laverni (ARG)
Atletico Junior – Bolivar
Referee: Juan Soto (VEN)
Assistant Referee 1: Rafael Yanez (VEN)
Assistant Referee 2: Jorge Urrego (VEN)
Fourth Official: Juan Restrepo (COL)