Referee: Francisco Chacon (MEX, photo)
Assistant Referee 1: Jose Camargo (MEX)
Assistant Referee 2: Alberto Morin (MEX)
Fourth Official: Jose Penaloza (MEX)
7 March 2012
Seattle Sounders – Santos
Referee: Walter Quesada (CRC)
Assistant Referee 1: Leonel Leal (CRC)
Assistant Referee 2: Octavio Jara (CRC)
Fourth Official: Jeffrey Solis (CRC)
Toronto FC – Los Angeles Galaxy
Referee: Courtney Campbell (JAM)
Assistant Referee 1: Ricardo Morgan (JAM)
Assistant Referee 2: Kedlee Powell (JAM)
Fourth Official: Kevin Morrison (JAM)
8 March 2012
Metapan – Pumas
Referee: Walter Lopez (GUA)
Assistant Referee 1: Gerson Lopez (GUA)
Assistant Referee 2: Ronaldo De La Cruz (GUA)
Fourth Official: Oscar Reyna (GUA)