Union – Nacional
Referee: Piero Maza (CHI, photo)
Assistant Referee 1: Alejandro Molina (CHI)
Assistant Referee 2: Claudio Urrutia (CHI)
Fourth Official: Felipe Gonzalez (CHI)
VAR: Angelo Hermosilla (CHI)
AVAR: Yadir Acuna (COL)
Internacional – Colo Colo
Referee: Dario Herrera (ARG)
Assistant Referee 1: Gabriel Chade (ARG)
Assistant Referee 2: Maximiliano del Yesso (ARG)
Fourth Official: Pablo Echavarría (ARG)
VAR: Mauro Vigliano (ARG)
AVAR: Fernando Espinoza (ARG)
Ceara – The Strongest
Referee: Derlis Lopez (PAR)
Assistant Referee 1: Jose Cuevas (PAR)
Assistant Referee 2: Luis Onieva (PAR)
Fourth Official: Giancarlo Juliadoza (PAR)
VAR: Nicolas Gallo (COL)
AVAR: Nicolas Rodriguez (COL)
Melgar – Deportivo Cali
Referee: Facundo Tello (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Cristian Navarro (ARG)
Fourth Official: Nicolas Lamolina (ARG)
VAR: Juan Soto (VEN)
AVAR: Gery Vargas (BOL)
Santos – Deportivo Tachira
Referee: Kevin Ortega (PER)
Assistant Referee 1: Michael Orue (PER)
Assistant Referee 2: Jesus Sanchez (PER)
Fourth Official: Augusto Menéndez (PER)
VAR: Victor Carrillo (PER)
AVAR: Jonny Bossio (PER)
Lanus – Independiente Del Valle
Referee: Christian Garay (CHI)
Assistant Referee 1: Jose Retamal (CHI)
Assistant Referee 2: Edson Cisternas (CHI)
Fourth Official: Dilio Rodríguez (BOL)
VAR: Carlos Benitez (PAR)
AVAR: Fernando Lopez (PAR)
Sao Paulo – Universidad Catolica
Referee: Alexis Herrera (VEN)
Assistant Referee 1: Carlos Lopez (VEN)
Assistant Referee 2: Lubin Torrealba (VEN)
Fourth Official: Orlando Bracamonte (VEN)
VAR: John Perdomo (COL)
AVAR: John Leon (COL)
Atletico Goianense – Olimpia
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Alexander Guzman (COL)
Assistant Referee 2: Sebastian Vela (COL)
Fourth Official: John Hinestroza (COL)
VAR: Julio Bascunan (CHI)
AVAR: Rodrigo Carvajal (CHI)