Atletico Mineiro – Emelec
Referee: Jesus Valenzuela (VEN, photo)
Assistant Referee 1: Jorge Urrego (VEN)
Assistant Referee 2: Tulio Moreno (VEN)
Fourth Official: Angel Arteaga (VEN)
VAR: Julio Bascunan (CHI)
AVAR: Rodrigo Carvajal (CHI)
Libertad – Athletico Paranaense
Referee: Andres Cunha (URU)
Assistant Referee 1: Richard Trinidad (URU)
Assistant Referee 2: Andres Nievas (URU)
Fourth Official: Guillermo Guerrero (ECU)
VAR: Carlos Orbe (ECU)
AVAR: Christian Lescano (ECU)
Boca Juniors – Corinthians
Referee: Andres Matonte (URU)
Assistant Referee 1: Nicolas Taran (URU)
Assistant Referee 2: Martin Soppi (URU)
Fourth Official: Jose Burgos (URU)
VAR: Leodan Gonzalez (URU)
AVAR: Gustavo Tejera (URU)
Colon – Talleres
Referee: Anderson Daronco (BRA)
Assistant Referee 1: Fabricio Vilarinho (BRA)
Assistant Referee 2: Rafael Alves (BRA)
Fourth Official: Luiz de Oliveira (BRA)
VAR: Wagner Reway (BRA)
AVAR: Rodrigo D’Alonso (BRA)
Palmeiras – Cerro Porteno
Referee: Patricio Loustau (ARG)
Assistant Referee 1: Juan Belatti (ARG)
Assistant Referee 2: Facundo Rodríguez (ARG)
Fourth Official: Yael Falcon (ARG)
VAR: Germán Delfino (ARG)
AVAR: Ezequiel Brailovsky (ARG)
Flamengo – Tolima
Referee: Mario Diaz de Vivar (PAR)
Assistant Referee 1: Milciades Saldivar (PAR)
Assistant Referee 2: Roberto Canete (PAR)
Fourth Official: Jose Mendez (PAR)
VAR: Eber Aquino (PAR)
AVAR: Eduardo Cardozo (PAR)
River Plate – Velez
Referee: Roberto Tobar (CHI)
Assistant Referee 1: Christian Schiemann (CHI)
Assistant Referee 2: Claudio Ríos (CHI)
Fourth Official: Nicolas Gamboa (CHI)
VAR: Rafael Traci (BRA)
AVAR: Braulio Machado (BRA)
Estudiantes – Fortaleza
Referee: Esteban Ostojich (URU)
Assistant Referee 1: Carlos Barreiro (URU)
Assistant Referee 2: Pablo Llarena (URU)
Fourth Official: Roberto Perez (PER)
VAR: Juan Lara (CHI)
AVAR: Angelo Hermosilla (CHI)