12 September 2017
Independiente – Atletico Tucuman
Referee: Andres Cunha (URU, photo)
Assistant Referee 1: Miguel Nievas (URU)
Assistant Referee 2: Horacio Ferreiro (URU)
Fourth Official: Cristian Ferreyra (URU)
Referee Assessor: Angel Sanchez (ARG)
14 September 2017
Santa Fe – Libertad
Referee: Diego Haro (PER)
Assistant Referee 1: Jonny Bossio (PER)
Assistant Referee 2: Coty Carrera (PER)
Fourth Official: Joel Alarcon (PER)
Referee Assessor: Rodolfo Otero (ARG)
19 September 2017
Estudiantes – Nacional
Referee: Raphael Claus (BRA)
Asistente 1Bruno Boschilia (BRA)
Assistant Referee 2: Kleber Gil (BRA)
Fourth Official: Wagner Reway (BRA)
Referee Assessor: Dario Ubriaco (URU)
Junior – Cerro Porteño
Referee: Dario Herrera (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Cristian Navarro (ARG)
Fourth Official: Fernando Espinoza (ARG)
Referee Assessor: Sandro Vera (ECU)
20 September 2017
Racing Club – Corinthians
Referee: Leodan Gonzalez (URU)
Assistant Referee 1: Mauricio Espinosa (URU)
Assistant Referee 2: Nicolas Taran (URU)
Fourth Official: Oscar Rojas (URU)
Referee Assessor: Jorge Jaimes (PER)
Flamengo – Chapecoense
Referee: Michael Espinoza (PER)
Assistant Referee 1: Stephen Atoche (PER)
Assistant Referee 2: Michael Orue (PER)
Fourth Official: Luis Garay (PER)
Referee Assessor: Claudio Cerdeira (BRA)
Ponte Preta – Sport Recife
Referee: Roddy Zambrano (ECU)
Assistant Referee 1: Byron Romero (ECU)
Assistant Referee 2: Juan Macias (ECU)
Fourth Official: Omar Ponce (ECU)
Referee Assessor: Ednilson Corona (BRA)
21 September 2017
LDU Quito – Fluminense
Referee: Fernando Rapallini (ARG)
Assistant Referee 1: Gabriel Chade (ARG)
Assistant Referee 2: Ariel Scime (ARG)
Fourth Official: Diego Abal (ARG)
Referee Assessor: Candelario Andarcia (VEN)