5 April 2016
Club America – Santos Laguna
Referee: Fernando Guerrero (MEX, photo)
Assistant Referee 1: Juan Rangel (MEX)
Assistant Referee 2: Andres Hernandez (MEX)
Fourth Official: Erick Miranda (MEX)
Tigres – Queretaro
Referee: Roberto Garcia (MEX)
Assistant Referee 1: Jose Camargo (MEX)
Assistant Referee 2: Alberto Morin (MEX)
Fourth Official: Jorge Rojas (MEX)