9 February 2016Universidad de Chile – River Plate
Referee: Carlos Vera (ECU, photo)
Assistant Referee 1: Christian Lescano (ECU)
Assistant Referee 2: Edwin Bravo (ECU)
Fourth Official: Juan Albarracin (ECU)
Referee Observer: Patricio Basualto (CHI)
Caracas – Huracan
Referee: Enrique Cáceres (PAR)
Assistant Referee 1: Rodney Aquino (PAR)
Assistant Referee 2: Carlos Cáceres (PAR)
Fourth Official: Eber Aquino (PAR)
Referee Observer: Bernanrdo Corujo (VEN)
10 February 2016
Sao Paulo – Cesar Vallejo
Referee: Christian Ferreyra (URU)
Assistant Referee 1: Nicolás Tarán (URU)
Asistente 2 Richard Trinidad (URU)
Fourth Official: Esteban Ostojich (URU)
Referee Observer: Nilson Moncao (BRA)
Racing – Puebla
Referee: Ricardo Marques (BRA)
Assistant Referee 1: Bruno Boschilia (BRA)
Assistant Referee 2: Guillerme Camilo (BRA)
Fourth Official: Raphael Claus (BRA)
Referee Observer: Luis Bongianino (ARG)
11 February 2016
Guarani – Independiente del Valle
Referee: Mauro Vigliano (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Diego Bonfa (ARG)
Fourth Official: Jorge Baliño (ARG)
Referee Observer: Carlos Alarcón (PAR)
Santa Fe – Oriente Petrolero
Referee: Víctor Carrillo (PER)
Assistant Referee 1: Raúl López (PER)
Assistant Referee 2: Jorge Yupanqui (PER)
Fourth Official: Michael Espinoza (PER)
Referee Observer: Pablo Montoya (COL)