Chivas Guadalajara – Deportivo Quito
Referee: Juan Soto (VEN, photo)
Assistant Referee 1: Jorge Urrego (VEN)
Assistant Referee 2: Carlos Lopez (VEN)
Fourth Official: Paul Delgadillo (MEX)
Defensor Sporting – Velez Sarsfield
Referee: Enrique Osses (CHI)
Assistant Referee 1: Carlos Astroza (CHI)
Assistant Referee 2: Juan Maturana (CHI)
Fourth Official: Hector Martinez (URU)
Fluminense – Arsenal
Referee: Antonio Arias (PAR)
Assistant Referee 1: Nicolas Yegros (PAR)
Assistant Referee 2: Hugo Martinez (PAR)
Fourth Official: Pericles Cortes (BRA)
8 February 2012
Nacional – Cruz Azul
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Gustavo Rossi (ARG)
Fourth Official: Enrique Caceres (PAR)
Union Espanola – Atletico Junior
Referee: Julio Quintana (PAR)
Assistant Referee 1: Rodney Aquino (PAR)
Assistant Referee 2: Dario Gaona (PAR)
Fourth Official: Claudio Puga (CHI)
Vasco da Gama – Nacional Montevideo
Referee: Jose Buitrago (COL)
Assistant Referee 1: Humberto Clavijo (COL)
Assistant Referee 2: Wilmar Navarro (COL)
Fourth Official: Marcelo Henrique (BRA)
9 February 2012
Internacional – Juan Aurich
Referee: Liber Prudente (URU)
Assistant Referee 1: Carlos Pastorino (URU)
Assistant Referee 2: Carlos Changala (URU)
Fourth Official: Leandro Vuaden (BRA)
Libertad – Alianza Lima
Referee: Martin Vazquez (URU)
Assistant Referee 1: Miguel Nievas (URU)
Assistant Referee 2: Marcelo Costa (URU)
Fourth Official: Carlos Amarilla (PAR)
Universidad Catolica – Bolivar
Referee: Patricio Loustau (ARG)
Assistant Referee 1: Hernan Maidana (ARG)
Assistant Referee 2: Gustavo Esquivel (ARG)
Fourth Official: Eduardo Gamboa (CHI)
Emelec – Olimpia
Referee: Wilmar Roldan (COL)
Assistant Referee 1: Eduardo Diaz (COL)
Assistant Referee 2: Alexander Guzman (COL)
Fourth Official: Alfredo Intriago (ECU)