Sport Huancayo – Arsenal
Referee: Martin Vazquez (URU, photo)
Assistant Referee 1: Mauricio Espinosa (URU)
Assistant Referee 2: Carlos Pastorino (URU)
Fourth Official: Henry Gambetta (PER)
Libertad – Nacional
Referee: Sergio Pezzotta (ARG)
Assistant Referee 1: Ricardo Casas (ARG)
Assistant Referee 2: Gustavo Esquivel (ARG)
Fourth Official: Enrique Caceres (PAR)
1 February 2012
Flamengo – Real Potosi
Referee: Victor Rivera (PER)
Assistant Referee 1: Cesar Escano (PER)
Assistant Referee 2: Raul Lopes Cruz (PER)
Fourth Official: Pericles Cortes (BRA)
Once Caldas – Internacional
Referee: Francisco Chacon (MEX)
Assistant Referee 1: Jose Camargo (MEX)
Assistant Referee 2: Juan Rangel (MEX)
Fourth Official: Sebastian Restrepo (COL)
2 February 2012
Caracas – Penarol
Referee: Sandro Ricci (BRA)
Assistant Referee 1: Dibert Pedrosa (BRA)
Assistant Referee 2: Marcelo Van Gasse (BRA)
Fourth Official: Mayker Gomez (VEN)
Tigres – Union Espanola
Referee: Saul Laverni (ARG)
Assistant Referee 1: Ariel Bustos (ARG)
Assistant Referee 2: Ernesto Uziga (ARG)
Fourth Official: Roberto Garcia (MEX)