Metropolitanos – Estudiantes de Merida
Referee: Juan Benitez (PAR, photo)
Assistant Referee 1: Rodney Aquino (PAR)
Assistant Referee 2: Roberto Canete (PAR)
Fourth Official: Derlis Lopez (PAR)
Referee Assessor: Miguel Buitrago (VEN)
VAR Supervisor: Juan Corozo (ECU)
Oriente Petrolero – Royal Pari
Referee: Augusto Aragon (ECU)
Assistant Referee 1: Byron Romero (ECU)
Assistant Referee 2: Christian Lescano (ECU)
Fourth Official: Guillermo Guerrero (ECU)
Referee Assessor: Pedro Saucedo (BOL)
VAR Supervisor: Sabrina Lois (ARG)
General Caballero – Sol de America
Referee: Piero Maza (CHI)
Assistant Referee 1: Alejandro Molina (CHI)
Assistant Referee 2: Carlos Lopez (VEN)
Fourth Official: Jose Argote (VEN)
Referee Assessor: Oscar Viera (PAR)
VAR Supervisor: Sergio Viola (ARG)
Melgar – Cienciano
Referee: Andres Rojas (COL)
Assistant Referee 1: Alexander Guzman (COL)
Assistant Referee 2: John Leon (COL)
Fourth Official: Carlos Ortega (COL)
Referee Assessor: Cesar Escano (PER)
VAR Supervisor: Sergio Cristiano (BRA)
Union La Calera – Nublense
Referee: Gery Vargas (BOL)
Assistant Referee 1: Jose Antelo (BOL)
Assistant Referee 2: Edwar Saavedra (BOL)
Fourth Official: Dilio Rodriguez (BOL)
Referee Assessor: Nilson Moncao (BRA)
River Plate – Liverpool
Referee: Nicolas Lamolina (ARG)
Assistant Referee 1: Jose Savorani (ARG)
Assistant Referee 2: Sebastian Ranieri (ARG)
Fourth Official: Laura Fortunato (ARG)
Referee Assessor: Carlos Pastorino (URU)
VAR Supervisor: Fredy Arellanos (PER)
LDU Quito – Mushuc Runa
Referee: Leodan Gonzalez (URU)
Assistant Referee 1: Carlos Barreiro (URU)
Assistant Referee 2: Horacio Ferreiro (URU)
Fourth Official: Anahi Fernandez (URU)
Referee Assessor: Juan Albarracin (ECU)
VAR Supervisor: Ana Oliveira (BRA)
Sport Boys – Ayacucho
Referee: Ivo Mendez (BOL)
Assistant Referee 1: Carlos Tapia (BOL)
Assistant Referee 2: Ariel Guizada (BOL)
Fourth Official: Cristian Aleman (BOL)
Referee Assessor: Jorge Jaimes (PER)
VAR Supervisor: Patricio Polic (CHI)
America de Cali – Independiente Medellin
Referee: Alexis Herrera (VEN)
Assistant Referee 1: Lubin Torrealba (VEN)
Assistant Referee 2: Alberto Ponte (VEN)
Fourth Official: Orlando Bracamonte (VEN)
Referee Assessor: Wilson Lamouroux (COL)
VAR Supervisor: Enrique Caceres (PAR)
Antofagasta – Union Espanola
Referee: John Ospina (COL)
Assistant Referee 1: Wilmar Navarro (COL)
Assistant Referee 2: John Gallego (COL)
Fourth Official: Carlos Betancur (COL)
Referee Assessor: Ricardo Casas (ARG)
Guairena – Nacional
Referee: Jose Argote (VEN)
Assistant Referee 1: Carlos Lopez (VEN)
Assistant Referee 2: Alejandro Molina (CHI)
Fourth Official: Piero Maza (CHI)
Referee Assessor: Manuel Bernal (PAR)
VAR Supervisor: Jairo Romero (VEN)
Deportivo La Guaira – Hermanos Colmenarez
Referee: Derlis Lopez (PAR)
Assistant Referee 1: Roberto Cañete (PAR)
Assistant Referee 2: Rodney Aquino (PAR)
Fourth Official: Juan Benitez (PAR)
Referee Assessor: Luiz Sanchez (VEN)
VAR Supervisor: Ana Perez (PER)
Guabira – Jorge Wilstermann
Referee: Guillermo Guerrero (ECU)
Assistant Referee 1: Christian Lescano (ECU)
Assistant Referee 2: Byron Romero (ECU)
Fourth Official: Augusto Aragon (ECU)
Referee Assessor: Oscar Maldonado (BOL)
VAR Supervisor: Olga Miranda (PAR)
Junior – La Equidad
Referee: Raphael Claus (BRA)
Assistant Referee 1: Kleber Gil (BRA)
Assistant Referee 2: Marcelo Van Gasse (BRA)
Fourth Official: Edina Alves (BRA)
Referee Assessor: Abraham Gonzalez (COL)
VAR Supervisor: Miguel Nievas (URU)
9 de Octubre – Delfin
Referee: Cristian Garay (CHI)
Assistant Referee 1: Jose Retamal (CHI)
Assistant Referee 2: Juan Serrano (CHI)
Fourth Official: Francisco Gilabert (CHI)
Referee Assessor: Luis Vera (ECU)
VAR Supervisor: Ednilson Corona (BRA)
Cerro Largo – Montevideo Wanderers
Referee: Kevin Ortega (PER)
Assistant Referee 1: Michael Orue (PER)
Assistant Referee 2: Jesus Sanchez (PER)
Fourth Official: Michael Espinoza (PER)
Referee Assessor: Juan Cardellino (URU)
VAR Supervisor: Luzmila Gonzalez (COL)