19-20 October 2021
Club Brugge – Manchester City
Referee: Antonio Nobre (POR, photo)
Assistant Referee 1: Luciano Maia (POR)
Assistant Referee 2: Nelson Pereira (POR)
Fourth Official: Jordy Vermeire (BEL)
Referee Observer: Guy Goethals (BEL)
Shakhtar Donetsk – Real Madrid
Referee: Julian Weinberger (AUT)
Assistant Referee 1: Sara Telek (AUT)
Assistant Referee 2: Stefan Pichler (AUT)
Fourth Official: Klym Zabroda (UKR)
Referee Observer: Volodymyr Petrov (UKR)
Beşiktaş JK – Sporting CP
Referee: Peter Kjaersgaard (DEN)
Assistant Referee 1: Dennis Rasmussen (DEN)
Assistant Referee 2: Jakob Mastrup (DEN)
Fourth Official: Çağdaş Altay (TUR)
Referee Observer: Murat Ilgaz (TUR)
AFC Ajax – Borussia Dortmund
Referee: Kristoffer Karlsson (SWE)
Assistant Referee 1: Niclas Ivarsson (SWE)
Assistant Referee 2: Marcus Klitte (SWE)
Fourth Official: Clay Ruperti (NED)
Referee Observer: Rene Temmink (NED)
Inter Milano – Sheriff Tiraspol
Referee: Lukas Fähndrich (SUI)
Assistant Referee 1: Jonas Erni (SUI)
Assistant Referee 2: Guillaume Maire (SUI)
Fourth Official: Giovanni Ayroldi (ITA)
Referee Observer: Antonio Damato (ITA)
Paris St. Germain – RB Leipzig
Referee: Duje Strukan (CRO)
Assistant Referee 1: Goran Perica (CRO)
Assistant Referee 2: Alen Jakšić (CRO)
Fourth Official: Romain Lissorgue (FRA)
Referee Observer: Stephane Lannoy (FRA)
FC Porto – AC Milan
Referee: Iwan Griffith (WAL)
Assistant Referee 1: Johnathon Bryant (WAL)
Assistant Referee 2: Ashley Davis (WAL)
Fourth Official: Gustavo Correia (POR)
Referee Observer: Lucilio Batista (POR)
Atletico de Madrid – Liverpool FC
Referee: Ivaylo Stoyanov (BUL)
Assistant Referee 1: Ivo Kolev (BUL)
Assistant Referee 2: Miroslav Maksimov (BUL)
Fourth Official: Pedro Munoz Piedra (ESP)
Referee Observer: Luis Medina Cantalejo (ESP)
FC Zenit – Juventus
Referee: Amine Kourgheli (BLR)
Assistant Referee 1: Juryj Chomčanka (BLR)
Assistant Referee 2: Viktar Hiecikaŭ (BLR)
Fourth Official: Yan Bobrovskiy (RUS)
Referee Observer: Yuri Baskakov (RUS)
Chelsea FC – Malmö FF
Referee: Kari a Hovdanum (FRO)
Assistant Referee 1: Marner Olsen (FRO)
Assistant Referee 2: Jogvan Breckmann (FRO)
Fourth Official: Carl Brook (ENG)
Referee Observer: Kenneth Clark (SCO)
FC Barcelona – Dynamo Kyiv
Referee: Alexandre Boucaut (BEL)
Assistant Referee 1: Florian Lemaire (BEL)
Assistant Referee 2: Quentin Lesceux (BEL)
Fourth Official: David Lopez Jimenez (ESP)
Referee Observer: Salustia Chato Cipres (AND)
Manchester United – Atalanta BC
Referee: Filip Glova (SVK)
Assistant Referee 1: Daniel Poláček (SVK)
Assistant Referee 2: Patrik Kmec (SVK)
Fourth Official: Anthony Backhouse (ENG)
Referee Observer: Stephen Lodge (ENG)
FC Salzburg – VfL Wolfsburg
Referee: Ondřej Pechanec (CZE)
Assistant Referee 1: Jan Hurych (CZE)
Assistant Referee 2: Dan Vodražka (CZE)
Fourth Official: Stefan Ebner (AUT)
Referee Observer: Robert Schörgenhofer (AUT)
LOSC Lille – Sevilla FC
Referee: Jorgen Burchardt (DEN)
Assistant Referee 1: Niels Hog (DEN)
Assistant Referee 2: Deniz Yurdakul (DEN)
Fourth Official: Bastien Dechepy (FRA)
Referee Observer: Alain Sars (FRA)
SL Benfica – Bayern München
Referee: Kai Erik Steen (NOR)
Assistant Referee 1: Jan Engan (NOR)
Assistant Referee 2: Ole Haukasen (NOR)
Fourth Official: Andre Narciso (POR)
Referee Observer: Joao Ferreira (POR)
BSC Young Boys – Villarreal CF
Referee: Joonas Jaanovits (EST)
Assistant Referee 1: Neeme Neemlaid (EST)
Assistant Referee 2: Thor Vaas (EST)
Fourth Official: Johannes von Mandach (SUI)
Referee Observer: Francesco Bianchi (SUI)