Colombia – Brazil
Referee: Patricio Loustau (ARG, photo)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Cristian Navarro (ARG)
Fourth Official: Fernando Echenique (ARG)
VAR: Piero Maza (CHI)
AVAR: Juan Lara (CHI)
Referee Assessor: Ubaldo Aquino (PAR)
Bolivia – Peru
Referee: Guillermo Guerrero (ECU)
Assistant Referee 1: Byron Romero (ECU)
Assistant Referee 2: Ricardo Baren (ECU)
Fourth Official: Luis Quiroz (ECU)
VAR: Carlos Orbe (ECU)
AVAR: Christian Lescano (ECU)
Referee Assessor: Roberto Perassi (BRA)
Venezuela – Ecuador
Referee: Andres Cunha (URU)
Assistant Referee 1: Richard Trinidad (URU)
Assistant Referee 2: Pablo Llanera (URU)
Fourth Official: Daniel Fedorczuk (URU)
VAR: Esteban Ostojich (URU)
AVAR: Juan Benitez (PAR)
Referee Assessor: Fredy Arellanos (PER)
Argentina – Uruguay
Referee: Roberto Tobar (CHI)
Assistant Referee 1: Christian Schiemann (CHI)
Assistant Referee 2: Claudio Rios (CHI)
Fourth Official: Nicolas Gamboa (CHI)
VAR: Julio Bascunan (CHI)
AVAR: Raul Orellana (CHI)
Referee Assessor: Jose Buitrago (COL)
Chile – Paraguay
Referee: Nestor Pitana (ARG)
Assistant Referee 1: Gabriel Chade (ARG)
Assistant Referee 2: Maximiliano Del Yesso (ARG)
Fourth Official: Dario Herrera (ARG)
VAR: John Ospina (COL)
AVAR: Alexander Guzman (COL)
Referee Assessor: Jorge Larrionda (URU)