Houston Dynamo – CD Guastatoya
Referee: Hector Martinez (HON, photo)
Assistant Referee 1: Jairo Morales (PUR)
Assistant Referee 2: Raymundo Feliz (DOM)
Fourth Official: William Anderson (PUR)
Referee Assessor: Leonel Leal (CRC)
Toronto FC – CA Independiente
Referee: Juan Calderon (CRC)
Assistant Referee 1: Juan Mora (CRC)
Assistant Referee 2: Carlos Fernandez (CRC)
Fourth Official: Benjamin Pineda (CRC)
Referee Assessor: George Ramsey (SKN)
Tigres UANL – Deportivo Saprissa
Referee: Joel Aguilar (SLV)
Assistant Referee 1: Juan Zumba (SLV)
Assistant Referee 2: Henry Pupiro (NCA)
Fourth Official: Trevester Richards (SKN)
Santos Laguna – CD Marathon
Referee: Drew Fischer (CAN)
Assistant Referee 1: Oscar Mitchell-Carvalho (CAN)
Assistant Referee 2: Michael Barwegen (CAN)
Fourth Official: Sherwin Johnson (GUY)
New York Red Bulls – CA Pantoja
Referee: John Pitti (PAN)
Assistant Referee 1: Alejandro Camarena (PAN)
Assistant Referee 2: Christian Ramirez (HON)
Fourth Official: Jose Kellys (PAN)
Monterrey – Alianza
Referee: David Gantar (CAN)
Assistant Referee 1: Chris Wattam (CAN)
Assistant Referee 2: Philippe Briere (CAN)
Fourth Official: Jose Torres (PUR)
Atlanta United – CS Herediano
Referee: Oshane Nation (JAM)
Assistant Referee 1: Nicholas Anderson (JAM)
Assistant Referee 2: Joseph Bertrand (JAM)
Fourth Official: Oliver Vergara (PAN)
Deportivo Toluca – Sporting Kansas City
Referee: Mario Escobar (GUA)
Assistant Referee 1: Gerson Lopez (GUA)
Assistant Referee 2: Humberto Panjoj (GUA)
Fourth Official: Bryan Lopez (GUA)