18 September 2018
AS Monaco – Atlético de Madrid
Referee: Stephan Klossner (SUI, photo)
Assistant Referee 1: Marco Zürcher (SUI)
Assistant Referee 2: Efe Kurnazca (SUI)
Fourth Official: Faouzi Benchabane (FRA)
Referee Observer: Fredy Fautrel (FRA)
FC Barcelona – PSV Eindhoven
Referee: Jérôme Brisard (FRA)
Assistant Referee 1: Benjamin Pagès (FRA)
Assistant Referee 2: François Boudikian (FRA)
Fourth Official: Rubén Ávalos Barrera (ESP)
Referee Observer: Luis Medina Cantalejo (ESP)
Inter Milano – Tottenham Hotspur
Referee: Antti Munukka (FIN)
Assistant Referee 1: Jouni Lemmettinen (FIN)
Assistant Referee 2: Turkka Joonas Valjakka (FIN)
Fourth Official: Lorenzo Illuzzi (ITA)
Referee Observer: Alfredo Trentalange (ITA)
Club Brugge – Borussia Dortmund
Referee: Nikola Dabanović (MNE)
Assistant Referee 1: Vladan Todorović (MNE)
Assistant Referee 2: Marjan Paunović (MNE)
Fourth Official: Jasper Vergoote (BEL)
Referee Observer: Michel Piraux (BEL)
Liverpool FC – Paris St. Germain
Referee: Alexander Harkam (AUT)
Assistant Referee 1: Andreas Staudinger (AUT)
Assistant Referee 2: Martin Höfler (AUT)
Fourth Official: Peter Wright (ENG)
Referee Observer: Peter Jones (ENG)
Crvena Zvezda – SSC Napoli
Referee: Adrien Jaccottet (SUI)
Assistant Referee 1: Vital Jobin (SUI)
Assistant Referee 2: Carmine Sangiovanni (SUI)
Fourth Official: Ivan Stamenković (SRB)
Referee Observer: Zoran Petrović (SRB)
Galatasaray – Lokomotiv Moskva
Referee: Enea Jorgji (ALB)
Assistant Referee 1: Emigers Gançi (ALB)
Assistant Referee 2: Dojando Myftari (ALB)
Fourth Official: Can Cengiz (TUR)
Referee Observer: Murat Ilgaz (TUR)
FC Schalke – FC Porto
Referee: Kristo Tohver (EST)
Assistant Referee 1: Silver Kõiv (EST)
Assistant Referee 2: Karolin Kaivoja (EST)
Fourth Official: Thorben Siewer (GER)
Referee Observer: Edgar Steinborn (GER)
19 September 2018
Shakhtar Donetsk – TSG Hoffenheim
Referee: Irfan Peljto (BIH)
Assistant Referee 1: Davor Beljo (BIH)
Assistant Referee 2: Amer Macić (BIH)
Fourth Official: Dmytro Panchyshyn (UKR)
Referee Observer: Volodymyr Petrov (UKR)
Viktoria Plzeň – CSKA Moskva
Referee: Peter Královič (SVK)
Assistant Referee 1: Miroslav Benko (SVK)
Assistant Referee 2: Erik Weiss (SVK)
Fourth Official: Vojtěch Severýn (CZE)
Referee Observer: Karel Bohuněk (CZE)
AFC Ajax – AEK Athens
Referee: Mohammed Al-Hakim (SWE)
Assistant Referee 1: Magnus Sjöblom (SWE)
Assistant Referee 2: Mikael Hallin (SWE)
Fourth Official: Martin van den Kerkhof (NED)
Referee Observer: Hans Reijgwart (NED)
SL Benfica – Bayern München
Referee: Stuart Attwell (ENG)
Assistant Referee 1: Constantine Hatzidakis (ENG)
Assistant Referee 2: Neil Davies (ENG)
Fourth Official: Rui Piteira Rodrigues (POR)
Referee Observer: Bernardino González Vázquez (ESP)
Manchester City – Olympique Lyonnais
Referee: Petr Ardeleánu (CZE)
Assistant Referee 1: Tomáš Mokrusch (CZE)
Assistant Referee 2: Petr Caletka (CZE)
Fourth Official: Martin Coy (ENG)
Referee Observer: Iain Robertson Brines (SCO)
Valencia – Juventus
Referee: Radu Petrescu (ROU)
Assistant Referee 1: Radu Ghinguleac (ROU)
Assistant Referee 2: Mircea Grigoriu (ROU)
Fourth Official: Saúl Ais Reig (ESP)
Referee Observer: Manuel López Fernández (ESP)
Real Madrid – AS Roma
Referee: Fábio Veríssimo (POR)
Assistant Referee 1: Paulo Soares (POR)
Assistant Referee 2: Nuno Pereira (POR)
Fourth Official: Valentín Pizarro Gómez (ESP)
Referee Observer: Manuel Díaz Vega (ESP)
Young Boys – Manchester United
Referee: Fran Jović (CRO)
Assistant Referee 1: Ivica Modrić (CRO)
Assistant Referee 2: Hrvoje Radić (CRO)
Fourth Official: David Schärli (SUI)
Referee Observer: Cyril Zimmermann (SUI)