Herediano – Tauro FC
Referee: Javier Santos (PUR, photo)
Assistant Referee 1: Hector Recinos (SLV)
Assistant Referee 2: Jairo Morales (PUR)
Fourth Official: William Anderson (PUR)
Monterrey – Municipal
Referee: Jose Pineda (HON)
Assistant Referee 1: Oscar Velasquez (HON)
Assistant Referee 2: Melvyn Cruz (HON)
Fourth Official: Erick Andino (HON)
Aguila – Toronto FC
Referee: Jose Rodriguez (PAN)
Assistant Referee 1: Daniel Williamson (PAN)
Assistant Referee 2: Keytzel Corrales (NCA)
Fourth Official: Jafeth Perea (PAN)
26 September 2012
W Connection – Guadalajara
Referee: David Rubalcaba (CUB)
Assistant Referee 1: Jaime Smith (PAN)
Assistant Referee 2: Jose Rodríguez (CUB)
Fourth Official: Marcos Brea (CUB)
Marathon – Caledonia
Referee: Cristophel Stewart (CAY)
Assistant Referee 1: Ionut Bordieanu (CAY)
Assistant Referee 2: Swason Owen (CAY)
Fourth Official: Kenville Titular (CAY)
Alajuelense – Real Esteli
Referee: Hector Rodriguez (HON)
Assistant Referee 1: Juan Lemus (GUA)
Assistant Referee 2: Marco Diaz (GUA)
Fourth Official: Wilson Da Costa (BAH)
27 September 2012
Puerto Rico Islanders – Isidro Metapan
Referee: Courtney Campbell (JAM)
Assistant Referee 1: Kedlee Powell (JAM)
Assistant Referee 2: Keble Williams (JAM)
Fourth Official: Valdin Legister (JAM)
FAS – Olimpia
Referee: Walter Quesada (CRC)
Assistant Referee 1: Octavio Jara (CRC)
Assistant Referee 2: Carlos Fernandez (CRC)
Fourth Official: Ricardo Montero (CRC)