Fortaleza – Libertad
Referee: Facundo Tello (ARG, photo)
Assistant Referee 1: Diego Bonfa (ARG)
Assistant Referee 2: Maximiliano Del Yesso (ARG)
Fourth Official: Nicolas Lamolina (ARG)
VAR: German Delfino (ARG)
AVAR: Cristian Navarro (ARG)
Defensa y Justicia – Emelec
Referee: Wilton Sampaio (BRA)
Assistant Referee 1: Danilo Manis (BRA)
Assistant Referee 2: Bruno Boschilia (BRA)
Fourth Official: Wagner Magalhaes (BRA)
VAR: Wagner Reway (BRA)
AVAR: Igor Benevenuto (BRA)
Newell's Old Boys – Corinthians
Referee: Andres Rojas (COL)
Assistant Referee 1: Dionisio Ruiz (COL)
Assistant Referee 2: David Fuentes (COL)
Fourth Official: Carlos Ortega (COL)
VAR: John Perdomo (COL)
AVAR: John Leon (COL)
Goias – Estudiantes La Plata
Referee: Gery Vargas (BOL)
Assistant Referee 1: Jose Antelo (BOL)
Assistant Referee 2: Edwar Saavedra (BOL)
Fourth Official: Ivo Mendez (BOL)
VAR: Carlos Orbe (ECU)
AVAR: Christian Lescano (ECU)
Guarani – Botafogo
Referee: Felipe Gonzalez (CHI)
Assistant Referee 1: Juan Serrano (CHI)
Assistant Referee 2: Miguel Rocha (CHI)
Fourth Official: Fernando Vejar (CHI)
VAR: Rodrigo Carvajal (CHI)
AVAR: Jose Cabero (CHI)
Sao Paulo – San Lorenzo
Referee: Esteban Ostojich (URU)
Assistant Referee 1: Martin Soppi (URU)
Assistant Referee 2: Andres Nievas (URU)
Fourth Official: Mathias De Armas (URU)
VAR: Andres Cunha (URU)
AVAR: Antonio Garcia (URU)
LDU Quito – Nublense
Referee: Yael Falcon (ARG)
Assistant Referee 1: Ezequiel Brailovsky (ARG)
Assistant Referee 2: Jose Savorani (ARG)
Fourth Official: Andres Merlos (ARG)
VAR: Hernan Mastrangelo (ARG)
AVAR: Pablo Gonzalez (ARG)
Red Bull Bragantino – America Mineiro
Referee: John Ospina (COL)
Assistant Referee 1: Sebastian Vela (COL)
Assistant Referee 2: John Gallego (COL)
Fourth Official: John Hinestroza (COL)
VAR: Yadir Acuna (COL)
AVAR: Mauricio Perez (COL)